Article: Spatial manipulation of magnetically-responsive nanoparticle engineered human neuronal progenitor cells
Journal: Nanomedicine: Nanotechnology, Biology and Medicine, August 2019, V. 20, P. 102038
Authors: Ivan Guryanov, Ekaterina Naumenko, Svetlana Konnova, Maria Lagarkova, Sergey Kiselev, Rawil Fakhrullin
In this study the interaction of neuronal precursor cells and neurons with polyelectrolyte-stabilized magnetic nanoparticles was described. The authors showed that magnetic nanoparticles accumulated in the cytoplasm and on the surface of neuronal progenitor cells, do not interact with the nuclear membrane and do not penetrate into the nucleus of neuronal cells. The possibility of directional movement of magnetically functionalized neuronal progenitor cells in a magnetic field has been demonstrated.