N.V. Feoktistova*, A.M. Mardanova**, G.F. Hadieva, M.R. Sharipova
Kazan Federal University, Kazan, 420008 Russia
E-mail: *nfeoktis@mail.ru, **mardanovaayslu@mail.ru
Received December 26, 2016
Full text PDF
Abstract
The paper is devoted to the usage of probiotics in the modern animal feed industry for solving pressing problems of animal nutrition. The general characteristics of probiotics and probiotic microorganisms have been given. The development of probiotics based on bifidobacteria, lactobacilli, Escherichia coli, and other microorganisms has been presented. Questions related to the expediency of probiotics in poultry farming have been considered. It has been noted that probiotics are characterized as a mandatory component of the pharmacological support of industrial poultry farming. Particular attention has been paid to the action and safety issues of applying spore probiotics. Veterinary spore probiotics developed in Russia have been described and characterized. Data on the positive effect of these biopreparations in poultry farming have been presented. The crucial role of domestic probiotics on the basis of Bacillus species for solving the urgent problems of Russian industrial poultry farming has been assessed. The characteristics of phytates as compounds with anti-nutritional properties have been provided. The need of phytases in poultry farming as feed additives for increasing the nutritional value of grain feeds has been shown. The general producers of acid phytases, which are part of commercial fodder preparations have been listed. The prospects and necessity of using probiotics based on bacteria of the genus Bacillus with phytase activity have been analyzed. The results of our own studies on the isolation and characterization of the β-propeller phytase of Bacillus ginsengihumi have been discussed.
Keywords: probiotics, poultry breeding, spore bacteria, bacterial enzymes, phytases, food additives
Acknowledgments. This study was funded by the subsidy allocated to Kazan Federal University as part of the state program for increasing its competitiveness among the world's leading centers of science and education and supported by the Russian Science Foundation (project no. 16-16-04062).
References
- The Modern Encyclopedia of Russian Industry – Plants and Their Products, Suppliers, Industrial Expositions. Available at: http://www.wiki-prom.ru. (In Russian)
- Castanon J.I.R. History of the use of antibiotic as growth promoters in European poultry feeds. Poult. Sci., 2007, vol. 86, no. 11, pp. 2466–2471. doi: 10.3382/ps.2007-00249.
- Graham J.P., Boland J.J., Silbergeld E. Growth promoting antibiotics in food animal production: An economic analysis. Public Health Rep., 2007, vol. 122, no. 1, pp. 79–87.
- Park Y.H., Hamidon F., Rajangan Ch., Soh K.P., Gan Ch.Yu., Lim Th.S., Abdullah W.N.W., Liong M.T. Application of probiotics for the production of safe and high-quality poultry meat. Korean J. Food Sci. Anim. Resour., 2016, vol. 36, no. 5, pp. 567–576. doi: 10.5851/kosfa.2016.36.5.567.
- Baranovskii Yu.A., Kondrashina E.A. Dysbacteriosis and Intestinal Dysbiosis. St. Petersburg, Piter, 2008. 224 p. (In Russian)
- Hawrelak J.A., Myers S.P. The causes of intestinal dysbiosis: A review. Altern. Med. Rev., 2004, vol. 9, no. 2, pp. 180–187.
- Fuller R. Probiotics in man and animals. J. Appl. Bacteriol., 1989, vol. 66, no. 5, pp. 365–378.
- Nozdrin G.A., Ivanova A.B., Shevchenko A.I., Nozdrin A.G. Scientific Grounds for Use of Probiotics in Poultry Breeding. Novosibirsk, Izd. Novosib. Gos. Agrar. Univ., 2005. 222 p. (In Russian)
- Pokhilenko V.D., Perelygin V.V. Probiotics based on spore-forming bacteria and their safety. Khim. Biol. Bezop., 2007, no. 2–3, pp. 20–41. (In Russian)
- Kablucheeva-Pashnik T.I., Koshchaev A.G. Pharmacological Justification of Using Probiotics in Poultry Breeding. Krasnodar, Izd. KubGAU, 2016. 270 p. (In Russian)
- Collins M.D., Gibson G.R. Рrobiocics, prebiotics, and synbiotics: Approaches for modulating the microbial ecology of the gut. Am. J. Clin. Nutr., 1999, vol. 69, no. 5, pp. 1052S–1057S.
- De Vrese M., Schrezenmeir J. Probiotics, prebiotics, and synbiotics. Adv. Biochem. Eng./Biotechnol., 2008, vol. 111, pp. 1–66. doi: 10.1007/10_2008_097.
- Goncharova G.I. Bifidoflora of humans, its protective role in the body and justification of usage of the Bifidumbacterin preparation. Extended Abstract of Doct. Biol. Sci. Diss. Moscow, 1982. 39 p. (In Russian)
- Topuriya L.Yu., Topuriya G.M., Grigor'eva G.V. Pharmacological Aspects of Using Probiotics in Breeding Broiler Chickens. Orenburg, Izd. Tsentr VNIIMS, 2012. 95 p. (In Russian)
- Patel R., DuPont H.L. New approaches for bacteriotherapy: Prebiotics, new generation probiotics, and synbiotics. Clin. Infect. Dis., 2015, vol. 60, suppl. 2, pp. S108–S121. doi: 10.1093/cid/civ177.
- Gupta V., Garg R. Probiotics. Indian J. Med. Microbiol., 2009, vol. 27, no. 3, pp. 202–209. doi: 10.4103/0255-0857.53201.
- Sánchez B., Delgado S., Blanco-Míquez A., Lourenço A., Gueimonde M., Margolles A. Probiocitcs, gut microbiota, and their influence on host health and disease. Mol. Nutr. Food Res., 2017, vol. 61, no. 1. doi: 10.1002/mnfr.201600240.
- Dylag K., Hubalewska-Mazgai M., Surmiak M., Szmyd J., Brzozowski T. Probiotics in the mechanism of protection against gut inflammation and therapy of gastrointestinal disorders. Curr. Pharm. Des., 2014, vol. 20, no. 7, pp. 1149–1155.
- Nagpal R., Kumar A., Kumar M., Behare P.V., Jain S., Yadav H. Probiotics, their health benefits and applications for developing healthier foods: A review. FEMS Microbiol. Lett., 2012, vol. 334, no. 1, pp. 1–15. doi: 10.1111/j.1574-6968.2012.02593.x.
- Ushakova N.A., Nekrasov R.V., Pravdin V.G., Kravtsova L.Z., Bobrovskaya O.I., Pavlov D.S. New generation of probiotic preparations for feeding purposes. Fundam. Issled., 2012, no. 1, pp. 184–192. (In Russian)
- Lin L., Zhang J. Role of intestinal microbiota and metabolites on gut homeostasis and human diseases. BMC Immunol., 2017, vol. 18, no. 2. doi: 10.1186/s12865-016-0187-3.
- Danilevskaya N.V. Pharmacological aspects of using probiotics. Veterinariya, 2005, no. 11, pp. 6–9. (In Russian)
- Malik N.I. Probiotics: Theoretical and practical aspects. Ptitsefabrika, 2006, no. 1, pp. 20–26. (In Russian)
- Panin A.I. Probiotics is an integral component of rational feeding of animals and birds. Ptitsa Ptitseprod., 2008, no. 3, pp. 13–16. (In Russian)
- Dmitrieva M.E. Veterinary welfare as the guaranty of cost-effective operation in the poultry sector. Ptitsa Ptitseprod., 2014, no. 1, pp. 23–25. (In Russian)
- Kablucheeva T.I. Diseases of Birds in Tables and Schemes. Krasnodar, Izd. Krasnodar. Gos. Univ., Kniga, 2008. 191 p. (In Russian)
- Huyghebaert G., Ducatelle R., Van Immerseel F. An update on alternatives to antimicrobial growth promoters for broilers. Vet. J., 2011, vol. 187, no. 2, pp. 182–188. doi: 10.1016/j.tvjl.2010.03.003.
- Nikulin V.N., Tarakanov B.V., Gerasimenko V.V. The Biological Grounds of Using Probiotic Preparations in Agriculture. Orenburg, Izd. Tsentr OGAU, 2007. 112 p. (In Russian)
- Gindullin A.I., Tremasov M.Ya., Beletskii S.O., Gindullina D.A. Probiotics based on Lactobacterium and Bacillus at T2 toxicosis of chickens. Ptitsa Ptitseprod., 2014, no. 3, pp. 44–46. (In Russian)
- Donkova N.V. Morphofunctional development specifics of broiler chickens. Veterinariya, 2004, no. 10, pp. 48–50. (In Russian)
- Surai P.F., Fisinin V.I. Modern methods to prevent stress in poultry breeding: from antioxidants to sirtuins and vitagenes. Mater. XVII Mezhdunar. konf. VNAP “Innovatsionnye razrabotki i ikh osvoenie v promyshlennom ptitsevodstve” [Proc. XVII Int. Conf. of the Global Poultry Research Association “Innovative Developments and Their Exploitation in Industrial Poultry Breeding”]. Sergiev Posad, 2012, pp. 24–34. (In Russian)
- Vasil'ev S.S., Korneva G.V. Morphofunctional changes in the immune system of broiler chickens during the breeding process. Uch. Zap. Kazan. Gos. Akad. Vet. Med. im. N. E. Baumana, 2010, no. 201, pp. 182–186. (In Russian)
- Bakulina L.F., Timofeev I.V., Perminova N.G., Plushkina A.F., Pechorkina N.I. Probiotics based on spore forming microorganisms of the genus Bacillus and their use in veterinary medicine. Biotekhnologiya, 2001, no. 2, pp. 48–56. (In Russian)
- Osipova I.G., Mikhailova N.A., Sorokulova I.B., Vasil'eva E.A., Gaiderov A.A. Spore probiotics, Zh. Mikrobiol. Epidemiol. Immunol., 2003, no. 3, pp. 113–119. (In Russian)
- Hong H.A., Ducle L.H., Cutting S.M. The use of bacterial spore formers as probiotics. FEMS Microbiol. Rev., 2005, vol. 29, no. 4, pp. 813–835. doi: 10.1016/j.femsre.2004.12.001.
- Belyavskaya V.A., Kashperova T.A., Bondarenko V.M., Il'ichev A.A., Sorokulova I.B., Malik N.I. Experimental evaluation of the biosafety of genetically engineered bacteria based on the model of Bacillus subtilis strain producing interferon. Zh. Mikrobiol. Epidemiol. Immunol., 2001, no. 2, pp. 16–20. (In Russian)
- Elfimova I.A., Yasnikov S.V., Perov A.N. Intestevit and Pioner biofodder for increasing the survivability of young animals. Veterinariya, 2006, no. 7, pp. 16–17. (In Russian)
- Baiguzina F.A., Alsynbaev M.M., Shtroman G.A., Kulagin V.F., Osipova I.G., Baiguzina S.N. Medicinal preparation out of Bacillus bacteria. Patent RF no. 2181596. Byull. Izobret., 2002, no. 12. (In Russian)
- Koshchaev A.G. The efficiency of Batsell and Monosporin food additives for raising broiler chickens. Veterinariya, 2007, no. 1, pp. 16–17. (In Russian)
- Neminushchaya L.A. The technology of producing and ensuring the quality of Lactosubtil Forte and Avilac Forte synbiotics, efficiency of their application in poultry breeding. Extended Abstract of Doct. Biol. Sci. Diss. Shchelkovo, 2011. 50 p. (In Russian)
- Lelyak A.I., Nozdrin G.A. The dry form of the Vetotsil therapeutic and preventive probiotic preparation. Patent RF no. 43767, 2005. (In Russian)
- Korotchenya I.N., Koburneev I.V., Ginzburg A.S., Lukhvich K.A. Bacillus licheniformis bacteria strain used for making probiotic supplement feed used for producing high-quality fodder improving performance and reducing risk of gastrointestinal disturbances in animals, birds, and fishes. Patent RF no. 2398872. Byull. Izobret., 2010, no. 25. (In Russian)
- Podbereznyi V.V., Polyantsev N.I. Effect of endobacterin on immune status of the organism and parenchymal organs in cows with mastitis. S-kh. Biol., 1994, no. 6, pp. 106–111. (In Russian)
- Grudinina T.N., Laptev G.Yu., Prokop'eva V.I., Soldatova V.V., Provorov E.L. Bacillus pantothenticus 1-85 strain for using in granulated forage. Patent RF no. 2235772 S1, 2004. (In Russian)
- Nikitenko L.I., Nikitenko V.I. Bacillus sp. strain is a component of the therapeutic and preventive preparation against dysbacteriosis and allergy. Inventor's Certificate no. 1710575 SU. Byull. Izobret., 1992, no. 5. (In Russian)
- Kulakov G.V., Irenkov I.P., Iliesh V.D. Bacillus subtilis strain used to produce a probiotic preparation for prevention and treatment of gastrointestinal disturbances in animals, poultry, and fish. Patent RF no. 2184774, 2002. (In Russian)
- Grigor'eva E.V. Morphofunctional evaluation of the effect of Olin probiotic on broiler chickens. Diss. Cand. Biol. Sci. Orenburg, 2013. 164 p. (In Russian)
- Belyavskaya V.A., Kashperova T.A., Sorokulova I.B., Smirnov V.V., Il'ichev A.A., Panin A.N., Malik N.I., Sandakhchiev L.S. Probiotic preparation with complex effect. Patent RF no. 2159625, 2000. (In Russian)
- Volkov M.Yu., Buyanovskaya N.Ya. Toxisporin probiotic preparation for viral and bacterial infections, method for preparing it, Bacillus licheniformis bacterial strain used as an ingredient of the probiotic preparation. Patent RF no. 2471864 S1, Byull. Izobret., 2013, no. 1. (In Russian)
- Nikolicheva T.A., Tarakanov T.V., Bravova G.B., Gavrilova N.N., Belevich E.I. Association of microorganisms for feeding young cattle. Inventor's Certificate no. 1043165, Byull. Izobret., 1991, no. 31. (In Russian)
- Zelenskaya O.Z. The effect of Sel-Plex + Batsell combination on broiler productivity. Agrar. Vestn. Urala, 2010, no 11–2, pp. 24–25. (In Russian)
- Osipova I.G., Sorokulova I.B., Vasil'eva E.A., Budanova E.V. Pre-clinical trials of new spore probiotics. Vestn. Ross. Akad. Med. Nauk, 2005, no. 12, pp. 36–40. (In Russian)
- Svetoch E.A., Stern N., Eruslanov B.V., Kovalev Y.N., Volodina L.I., Perelygin V.V., Mitsevich I.P., Pokhilenko V.D., Borzenkov V.N., Levchuk V.P., Svetoch E.O., Kudriavtseva T.Y. Isolation of Bacillus circulans and Paenibacillus polymyxa strains inhibitory to Campylobacter jejuni and characterization of associated bacteriocins. J. Food Prot., 2005, vol. 68, no. 1, pp. 11–17.
- Nozdrin G.A., Ivanova A.B., Shevchenko A.I., Shevchenko S.A. Probiotics and Micronutrients during Intensive Breeding of Chickens of the Smena Cross. Novosibirsk, Izd. NGAU, 2009. 207 p. (In Russian)
- Knap I., Kehlet A.B., Bennedsen M., Mathis G.F., Hofacre C.L., Lumpkins B.S., Jensen M.M., Raun M., Lay A. Bacillus subtilus (DSM17299) significantly reduced Salmonella in broilers. Poult. Sci., 2011, vol. 90, no. 8, pp. 1690–1694. doi: 10.3382/ps.2010-01056.
- Bai K., Huang Q., Zhang J., He J., Zhang L., Wang T. Supplemental effects of probiotic Bacillus subtilis fmbJ on growth performance, antioxidant capacity, and meat quality of broiler chickens. Poult. Sci., 2017, vol. 96, no. 1, pp. 74–82.
- Novak R., Bogovič Matijašić B., Terčič D., Cervek M., Gorjanc G., Holcman A., Levart A., Rogelj I. Effects of two probiotic additives containing Bacillus spores on carcass characteristics, blood lipids and cecal volatile fatty acids in meat type chickens. J. Anim. Physiol. Anim. Nutr., 2011, vol. 95, no. 4, pp. 423–433. doi: 10.1111/j.1439-0396.2010.01068.x.
- Liu X., Yan H., Lv L., Xu Q., Yin Ch., Zhang K., Wang P., Hu J. Growth performance and meat quality of broiler chickens supplemented with Bacillus licheniformis in drinking water. Asian-Australas. J. Anim. Sci., 2012, vol. 25, no. 5, pp. 682–689. doi: 10.5713/ajas.2011.11334.
- Fan Y., Zhao L., Ma Q., Li X., Shi H., Zhou T., Zhang J., Ji C. Effects of Bacillus subtilis ANSB060 on growth performance, meat quality and aflatoxin residues in broilers fed moldy peanut meal naturally contaminated with aflatoxins. Food Chem. Toxicol., 2013, vol. 59, pp. 748–753. doi: 10.1016/j.fct.2013.07.010.
- Li Y.B., Xu Q., Huang Z., Lv L., Liu X., Yin C., Yan H., Yuan J. Effects of Bacillus subtilis CGMCC 1.1086 on the growth performance and intestinal microbiota of broilers. J. Appl. Microbiol., 2016, vol. 120, no. 1, pp. 195–204. doi: 10.1111/jam.12972.
- Kim H.W., Yan F.F., Hu J.Y., Cheng H.W., Kim Y.H. Effects of probiotics feeding on meat quality of chicken breast during postmortem storage. Poult. Sci., 2016, vol. 95, no. 6, pp. 1457–1464. doi: 10.3382/ps/pew055.
- Mukhametzyanova A.D., Akhmetova A.I., Sharipova M.R. Microorganisms as phytase producers. Microbiology, 2012, vol. 81, no. 3, pp. 267–275. doi: 10.1134/S0026261712030095.
- Balaban N.P., Suleimanova A.D., Valeeva L.R., Shakirov E.V., Sharipova M.R. Structural characteristics and catalytic mechanism of Bacillus β-propeller phytases. Biochemistry (Moscow), 2016, vol. 81, no. 8, pp. 785–793. doi: 10.1134/S0006297916080010.
- Dersjant-Li Y., Awati A., Schulze H., Partridge G. Phytase in non-ruminant animal nutrition: A critical review on phytase activities in the gastrointestinal tract and influencing factors. J. Sci. Food Agric., 2015, vol. 95, no. 5, pp. 878–896. doi: 10.1002/jsfa.6998.
- Selle P.H., Ravindran V. Microbial phytase in poultry nutrition. Anim. Feed Sci. Technol., 2007, vol. 135, nos. 1–2, pp. 1–41. doi: 10.1016/j.anifeedsci.2006.06.010.
- Andrianova E.N. Scientific justification for increasing the efficiency of using fodders during egg and poultry meat production. Extended Abstract of Doct. Agric. Sci. Diss., Sergiev Posad, 2013. 44 p. (In Russian)
- Woyengo T.A., Nyachoti C.M. Review: Anti-nutritional effects of phytic acid in diets for pigs and poultry – current knowledge and directions for future research. Can. J. Anim. Sci., 2013, vol. 93, no. 1, pp. 9–21. doi: 10.4141/cjas2012-017.
- Yu S., Cowieson A., Gilbert C., Plumstead P., Dalsgaard S. Interactions of phytate and myo-inositol phosphate esters (IP1-5) including IP5 isomers with dietary protein and iron and inhibition of pepsin. J. Anim. Sci., 2012, vol. 90, no. 6, pp. 1824–1832. doi: 10.2527/jas.2011-3866.
- Ptak A., Bedford M.R., Świątkiewicz S., Žyła K., Józefiak D. Phytase modulates ideal microbiota and enhances growth performance of the broiler chickens. PLoS One, 2015, vol. 10, no. 3, art. e0119770, pp. 1–15. doi: 10.3389/fmicb.2016.02033.
- Borda-Molina D., Vital M., Sommerfeld V., Rodehutscord M., Camarinha-Silva A. Insights into broilers' gut microbiota fed with phosphorus, calcium, and phytase supplemented diets. Front. Microbiol., 2016, vol. 7, art. 2033, pp. 1–13. doi: 10.3389/fmicb.2016.02033.
- Lei X.G., Weaver J.D., Mullaney E., Ullah A.H., Azain M.J. Phytase, a new life for an “old” enzyme. Annu. Rev. Anim. Biosci., 2013, vol. 1, pp. 283–309. doi: 10.1146/annurev-animal-031412-103717.
- Sinitsyna O.A., Fedorova E.A., Gusakov A.V., Uporov I.V., Sokolova L.M., Bubnova T.M., Okunev O.N., Chulkin A.M., Vinetskii Yu.P., Sinitsyn A.P. Isolation and characterization of extracellular phytase from Penicillium canescens. Biokhmiya, 2006, vol. 7, no. 9, pp. 1260–1268. (In Russian)
- Vybornaya T.V., Larina A.S., Sineokii S.P., Fedorov A.S., Yuzbashev T.V., Yuzbasheva E.Yu. Recombinant strain of Yarrowia lipolytica yeast as a phytase producer. Patent RF no. 2504579. Byull. Izobret., 2014, no. 2. (In Russian)
- Gordeeva T.I., Borshchevskaya L.N., Sineokii S.P. Mutant recombinant thermally stable phytase (variants), DNA fragment coding this phytase (variants), Pichia pastoris strain producing this phytase (variants). Patent RF no. 2472855 S2, 2013. (In Russian)
- Apajalahti J., Heikkinen P., Kerovuo J., Laureus M., Morgan E., Nurminen P., Siikanen O. Phytase from Bacillus subtilis, gene encoding this phytase, method for its preparing and application. Patent RF no. 2227159, 2004. (In Russian)
- Knap I., Knarreborg A., Leser T.D., Lunn B. Bacillus subtilis strain with the high level of phytase production (variants), composition for feeding animals, and way to feed animals. Patent RF no. 2506307 S2, Byull. Izobret., 2014, no. 4.
- Akhmetova A.I., Nyamsuren Ch., Balaban N.P., Sharipova M.R. Isolation and characterization of a new bacillary phytase. Russ. J. Bioorg. Chem., 2013, vol. 39, no. 4, pp. 384–389. doi: 10.1134/S1068162013040031.
- Akhmetova A.I. β-propeller phytase Bacillus ginsengihumi: Gene cloning, protein purification, and enzyme properties. Extended Abstract of Cand. Biol. Sci. Diss., Kazan, 2013. 26 p. (In Russian)
- Cutting S.M. Bacillus probiotics. Food Microbiol., 2011, vol. 28, no. 2, pp. 214–220. doi: 10.1016/j.fm.2010.03.007.
For citation: Feoktistova N.V., Mardanova A.M., Hadieva G.F., Sharipova M.R. Probiotics based on bacteria from the genus Bacillus in poultry breeding. Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki, 2017, vol. 159, no. 1, pp. 85–107. (In Russian)

The content is available under the license Creative Commons Attribution 4.0 License.