2025
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Masson P, Pashirova T., Affinity Electrophoresis of Proteins for Determination of Ligand Affinity and Exploration of Binding Sites//International Journal of Molecular Sciences. - 2025. - Vol.26, Is.7. - Art. №3409.
ijms_26_03409.pdf -
Hajimohammadi S. New views on physiological functions and regulation of butyrylcholinesterase and potential therapeutic interventions / S. Hajimohammadi, O. Lockridge, P. Masson // Front Mol Biosci. - 2025. - 12. - P.1625318, 10.3389/fmolb.2025.1625318
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Shaihutdinova Z.M, Pashirova T.N, Masson P., Slow-binding inhibitors of enzymes: kinetic characteristics and pharmacological interest//Biomeditsinskaia khimiia. - 2025. - Vol.71, Is.2. - P.81-94.
2024
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Mukhametgalieva A, Mir S.A, Shaihutdinova Z, Human Plasma Butyrylcholinesterase Hydrolyzes Atropine: Kinetic and Molecular Modeling Studies//Molecules. - 2024. - Vol.29, Is.9. - Art. №2140.
molecules_29_02140_v2.pdf -
Pashirova T, Salah-Tazda?t R, Tazda?t D, Applications of Microbial Organophosphate-Degrading Enzymes to Detoxification of Organophosphorous Compounds for Medical Countermeasures against Poisoning and Environmental Remediation//International Journal of Molecular Sciences. - 2024. - Vol.25, Is.14. - Art. №7822.
2024_Pashirova.pdf -
Varfolomeev S.D, ?vedas V.K, Efremenko E.N, Biocatalysis: modern challenges and applications//Russian Chemical Reviews. - 2024. - Vol.93, Is.12. - .
2024_Uspekhi_khimii.pdf -
Паширова Т.Н., Шайхутдинова З.М., Татаринов Д.А., Титова А.А., Васильева О.С., Маланьева А.Г., Массон П. Фармакокинетический мониторинг «свободной» и инкапсулированной в полимерсомы флуоресцентно-меченой IRD800CW-бутирилхолинэстеразы человека при внутривенном введении мышам // VI Международная научно-практическая конференция ПОСТГЕНОМ'2024 и XI Российский симпозиум «Белки и пептиды», 29 октября – 2 ноября 2024, Москва
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Pashirova T, Shaihutdinova Z, Tatarinov D, Pharmacokinetics and fate of free and encapsulated IRD800CW-labelled human BChE intravenously administered in mice//International Journal of Biological Macromolecules. - 2024. - Vol.282, Is.. - Art. №137305.
2024_IJBM.pdf -
Fetin P.A, Zorin I.M, Shaihutdinova Z.M, Polystyrene?Poly(acrylic acid) Block Copolymers for Encapsulation of Butyrylcholinesterase into Injectable Nanoreactors//Biomolecules. - 2024. - Vol.14, Is.12. - Art. №1555.
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Shaihutdinova Z, Masson P., Pre-Steady-State and Steady-State Kinetic Analysis of Butyrylcholinesterase-Catalyzed Hydrolysis of Mirabegron, an Arylacylamide Drug//Molecules. - 2024. - Vol.29, Is.10. - Art. №2356.
F_molecules_29_02356_v2.pdf -
Blinova A.R, Masson P, Kulakova A.M, Butyrylcholinesterase with altered catalytic triad, acting as a promising bioscavenger against organophosphorus agents//Molecular Physics. - 2024. - Vol., Is.. - Art. №e2387246.
2023
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Мухаметгалиева А.Р. Аномальное кинетическое поведение ацетилхолинэстеразы с бензоилхолином в качестве субстрата / Мухаметгалиева А.Р., Немтарев А.В., Сякаев В.В., Паширова Т.Н., Массон П. // ТЕЗИСЫ ДОКЛАДОВ
13-ой Международной научной конференции
«БИОКАТАЛИЗ. ФУНДАМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ
И ПРИМЕНЕНИЯ» (БИОКАТАЛИЗ - 2023). -
2023. - С. 199.
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Pashirova T.N, Shaihutdinova Z.M, Mironov V.F, Biomedical Nanosystems for In Vivo Detoxification: From Passive Delivery Systems to Functional Nanodevices and Nanorobots//Acta Naturae. - 2023. - Vol.15, Is.1-56. - P.4-12.
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Pashirova, T.N.; Shaihutdinova, Z.M.; Mansurova, M.N.; Kazakova, R.R.; Shambazova, D.N.; Bogdanov, A.V.; Tatarinov, D.A.; Daudé, D.; Jacquet, P.; Chabrière, E.; Akhunzianov A.A., Miftakhova R.R, P. Masson, Tuning the Envelope Structure of Enzyme Nanoreactors for In Vivo Detoxification of Organophosphates//International Journal of Molecular Sciences. - 2023. - Vol.24, Is.21. - Art. №15756.
- Masson P. Drug and pro-drug substrates and pseudo-substrates of human butyrylcholinesterase / P. Masson, Z. Shaihutdinova, O. Lockridge , Drug and pro-drug substrates and pseudo-substrates of human butyrylcholinesterase // Biochemical Pharmacology. - 2023. - 218. - 115910
- Masson P. Partial Reversible Inhibition of Enzymes and Its Metabolic and Pharmaco-Toxicological Implications / P. Masson, A.R. Mukhametgalieva // Int. J. Mol. Sci., 2023, 24(16), 12973
- Coccolini, C.DABCO-functionalized nanoemulsions with antimicrobial properties for potential treatment of ocular myasthenia gravis / C. Coccolini, E. Bersell, F. Fathi, M.B.P.P Oliveira, P. Masson, A.V. Bogdanov, T. Pashirova, K. Krambeck, E.B. Souto // Med. Sci. Forum, 2023, 2.
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Mukhametgalieva A.R, Nemtarev A.V, Sykaev V.V, Activation/Inhibition of Cholinesterases by Excess Substrate: Interpretation of the Phenomenological b Factor in Steady-State Rate Equation//International Journal of Molecular Sciences. - 2023. - Vol.24, Is.13. - Art. №10472.
2022
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Pashirova T. Enzyme Nanoreactor for In Vivo Detoxification of Organophosphates / T.N. Pashirova, Z.Shaihutdinova, M. Mansurova M., R. Kazakova, D. Shambazova, A. Bogdanov, D. Tatarinov, D. Daudé, P. Jacquet, E. Chabrière, P. Masson // ACS Appl Mater Interfaces. - 2022. - 14(17). - 19241-19252.
F_proof.pdf -
Shajhutdinova Z, Pashirova T, Masson P., Kinetic Processes in Enzymatic Nanoreactors for In Vivo Detoxification//Biomedicines. - 2022. - Vol.10, Is.4. - Art. №784.
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Lushchekina S.V, Nemukhin A.V, Polyakov I.V, Spontaneous Reactivation of OPC-Inhibited BChE Mutants: Modeling of Mechanisms//Russian Journal of Physical Chemistry B. - 2022. - Vol.16, Is.1. - P.103-108.
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Masson P, Lushchekina S., Conformational Stability and Denaturation Processes of Proteins Investigated by Electrophoresis under Extreme Conditions//Molecules. - 2022. - Vol.27, Is.20. - Art. №6861.
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Mukhametgalieva A.R, Lushchekina S.V, Aglyamova A.R, Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates//Biochimica et Biophysica Acta - Proteins and Proteomics. - 2022. - Vol.1870, Is.1. - Art. №140733.
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Pashirova T.N, Afonso A.B, Terekhova N.V, Nanogels for drug delivery: physicochemical properties, biological behavior, and in vivo applications//Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications. - 2022. - Vol., Is.. - P.95-131.
- Kazakova R.R., Masson P. Quantitative measurements of pharmacological and toxicological activity of molecules // Chemistry. – Vol. 4. – 2022. – P.1466-1474.
2021
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Pashirova T.N, Bogdanov A, Masson P., Therapeutic nanoreactors for detoxification of xenobiotics: Concepts, challenges and biotechnological trends with special emphasis to organophosphate bioscavenging//Chemico-Biological Interactions. - 2021. - Vol.346, - P. 109577.
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Zueva I, Lushchekina S, Shulnikova P, alpha-tocopherol, a slow-binding inhibitor of acetylcholinesterase//CHEMICO-BIOLOGICAL INTERACTIONS. - 2021. - Vol.348, Is.. - Art. №109646.
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Zueva I, Lenina O, Kayumova R, Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments//Chemico-Biological Interactions. - 2021. - Vol.345, Is.. - Art. № 109558.
2020
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Zueva I.V, Lushchekina S.V, DaudУЉ D, Steady-state kinetics of enzyme-catalyzed hydrolysis of echothiophate, a Pт??S bonded organophosphorus as monitored by spectrofluorimetry//Molecules. - 2020. - Vol.25, Is.6. - Art. № 1371.
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Lushchekina S.V, Masson P., Slow-binding inhibitors of acetylcholinesterase of medical interest//Neuropharmacology. - 2020. - Vol.177, Is.. - Art. № 108236.
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Masson P, Lushchekina S.V., Catalytic bioscavengers: The second generation of bioscavenger-based medical countermeasures//Handbook of Toxicology of Chemical Warfare Agents. - 2020. - Vol., Is.. - P.1199-1229.
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Lushchekina S.V, Inidjel G, Martinez N, Impact of sucrose as osmolyte on molecular dynamics of mouse acetylcholinesterase//Biomolecules. - 2020. - Vol.10, Is.12. - P.1-19.
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Zueva I.V, Lushchekina S.V, Pottie I.R, 1-(3-tert-butylphenyl)-2,2,2-trifluoroethanone as a potent transition-state analogue slow-binding inhibitor of human acetylcholinesterase: Kinetic, MD and QM/MM studies//Biomolecules. - 2020. - Vol.10, Is.12. - P.1-21.
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Lenina O.A, Zueva I.V, Zobov V.V, Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning//Scientific Reports. - 2020. - Vol.10, Is.1. - Art. № 16611.
2019
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Boyko K.M, Baymukhametov T.N, Chesnokov Y.M, 3D structure of the natural tetrameric form of human butyrylcholinesterase as revealed by cryoEM, SAXS and MD//Biochimie. - 2019. - Vol.156, Is.. - P.196-205.
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Zueva I, Dias J, Lushchekina S, New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease//Neuropharmacology. - 2019. - Vol.155, Is.. - P.131-141.
- Mukhametgalieva A.R., Zueva I.V., Aglyamova A.R., Lushchekina S.V., Masson P. A new sensitive spectrofluorimetric method for measurement of activity and kinetic study of cholinesterases // Biochim Biophys Acta Proteins Proteom. 2020 Jan; 1868(1):140270. doi: 10.1016/j.bbapap.2019.140270. Q1
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Goličnik M., Masson P., Time-course of enzyme-catalyzed competing substrate degradation for michaelian behavior and for enzymes showing activation/inhibition by excess substrate//Chemico-Biological Interactions. - 2019. - Vol.309, Is.. - Art. № 108704.
- Mukhametgalieva A.R., Aglyamova A.R., Lushchekina S.V., Goličnik M., Masson P. Time-course of human cholinesterases-catalyzed competing substrate kinetics // Chem Biol Interact. 2019 Sep 1; 310: 108702. doi: 10.1016/j.cbi.2019.06.015. Q1
2018
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Petrov K, Zueva I, Kovyazina I, C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies//Neuropharmacology. - 2018. - Vol.131, Is.. - P.304-315.
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Pashirova T.N, Zueva I.V, Petrov K.A, Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model//Colloids and Surfaces B: Biointerfaces. - 2018. - Vol.171, Is.. - P.358-367.
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Pashirova T.N, Bra?ki A, Zueva I.V, Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection//Journal of Controlled Release. - 2018. - Vol.290, Is.. - P.102-111.
2017
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Pashirova T.N, Zueva I.V, Petrov K.A, Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity//ACS Applied Materials and Interfaces. - 2017. - Vol.9, Is.20. - P.16922-16932.
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Lushchekina S.V, Ayupov R, Semenov V.E, Computational Exploration of Reactivity of 6-Methyluracil/Imidazole-2-Carbaldehyde Oxime Conjugate//BioNanoScience. - 2017. - Vol.7, Is.1. - P.229-232.
2016
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Elistratova J.G. Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6]4-/ J.G. Elistratova, A.R. Mustafina,K .A. Brylev, K.A. Petrov, M.A. Shestopalov, Y.V. Mironov, V.M. Babaev, I.K. Rizvanov, P. Masson, O.G. Sinyashin // Analyst. - 2016. - Vol.141, Is.13. - P.4204-4210.
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Mukhametshina A.R. Luminescent silica nanoparticles for sensing acetylcholinesterase-catalyzed hydrolysis of acetylcholine / A. R. Mukhametshina, S. V. Fedorenko, I. V. Zueva, K. A. Petrov, P. Masson, I. R. Nizameev, A. R. Mustafina, O.G. Sinyashin // Biosensors and Bioelectronics. - 2016. - V. 77. - P. 871-878.
2015
| Work address: | 9 Parizhskoy Kommuny Str., Kazan, Academic and Research Centre of the Institute of Fundamental Medicine and Biology |
| Office number: | 202 |
| E-mail: | PMasson@kpfu.ru |
| Google scholar: | https://scholar.google.ru/citations?hl=en&authuser=1&user=IwkPn08AAAAJ |
| Experience: |
| Experience: |
| Scientific and pedagogical experience: |
| General experience: |
| Experience in KFU: |
