New approaches in gene and cell therapy of humans and animals:

• Development of novel gene and cell preparations for the treatment of degenerative diseases in humans; 
• Development of new delivery systems of gene-based therapeutics into patient body;
• Tissue engineering for improved recovery after damages of nerve, spinal cord and musculoskeletal system. Gene and cell technologies for veterinary medicine

Biomarkers for infectious and autoimmune diseases:

• Hemorrhagic fever with renal syndrome (and other hemorrhagic fevers) - determination of biomarkers for diagnosis, identification of potential therapeutic targets for developing new therapies and drug screening;
• Autoimmune diseases - investigation of cytokines in the serum of patients with autoimmune diseases such as systemic lupus erythematosus, multiple sclerosis, rheumatoid arthritis;
• Development of various diagnostic systems and the search for new therapeutic targets;
• Crohn's disease and ulcerative colitis - determination of inflammatory signals leading to the migration of pro-inflammatory cells in the intestine. Identification of potential therapeutic targets;
• Plasmacytoid dendritic cells (PDC) in the pathogenesis of chronic fatigue syndrome (CFS), and Crohn's disease. Research of PDC contribution to the pathogenesis of diseases. Identification of the molecular mechanisms leading to the migration of PDC in the intestines of patients with CFS and Crohn's disease.

Genetically-cell technology to stimulate liver regeneration:

• Development of methods for isolation and cultivation of liver regional stem cells;
• Development of gene and cell preparations for the treatment of liver diseases.

Tumor metastasis

Research is focused on the fundamental molecular mechanisms regulating tumor metastasis and the role of circulating tumor cells in the metastatic process.

Stem tumor cells

Investigating the biology of stem tumor cells to better understand the phenomenon of resistance and provide the basis for the development of new cancer therapy.

Onco-Immunology

The immune system is the link between the tumor and the body. Understanding the molecular mechanisms that regulate the cellular and humoral immune response to tumors for development of novel therapeutic approaches.

Autophagy in oncology

Autophagy, or "self-eating", is the process by which cells are redistributed and metabolites contribute to cell survival, or induce their death. Autophagy, which supports tumor growth is a rational therapeutic target. The studies will help to understand the role of autophagy in tumor growth and creation of therapeutic products aimed at the inhibition/regulation of the process.