Deneka Alexander Yaroslavovich (архив)
Денека Александр Ярославович
- Short description of important scientific result: Dr. Deneka is conducting research, dedicated to investigation of the mechanisms by which intracellular regulatory proteins - stem cell markers, translational regulators (such as the Musashi family proteins) and scaffolding proteins (Nedd9) regulate growth, metastasis and response of human cancer cells targeted agents and chemotherapy. Recent work includes a functional analysis of complex signaling networks, the purpose of which is is to understand the causes of metastasis of non-small cell lung cancer. In collaboration with Dr. Y. Boumber at KFU and Dr. E.A. Golemis at the Fox Chase Cancer Center, the team identified Musashi 2 protein (MSI2) as a driver of progression of non-small cell lung cancer (NSCLC), and revealed its biological role in maintaining the activity of EGFR in EGFR-mutant NSCLC. These discoveries are of great scientific and practical importance, since resistance to targeted therapy of EGFR mutant NSCLC is steadily increasing, and further preclinical and, in the future,
- Unique identifier in the Web of Science (Researcher ID): http://www.researcherid.com/rid/Q-7273-2017
- Unique identifier in the Scopus (Author ID): http://www.scopus.com/authid/detail.url?authorId=56703288700
- Quantity of published work in Scopus: 9
- Quantity of reference on published work in Scopus: 51
- Personal index of Hirsh: 4
- Unique identifier in the Elibrary (Author ID): http://elibrary.ru/author_items.asp?authorid=1019720
- Unique identifier in the ORCID (ORCID ID): http://orcid.org/0000-0003-2448-5156
| Work address: | 18 Kremlevskaya Str., Kazan, Building #02 (Eastern wing of the University's main building) |
| Office number: | 104В |
| Phone: | 2337842 |
| E-mail: | AYDeneka@kpfu.ru |
| Google scholar: | https://scholar.google.com/citations?user=ynRoB1kAAAAJ&hl=ru |
