Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
HUMAN ADIPOSE DERIVED STEM CELLS DO NOT AL­TER CYTOKINE SECRETION IN RESPONSE TO THE GENETIC MODIFICATION WITH PEGFP-N2 PLASMID DNA
Form of presentationArticles in international journals and collections
Year of publication2013
Языканглийский
  • Martynova Ekaterina Vladimirovna, author
  • Rizvanov Albert Anatolevich, author
  • Salafutdinov Ilnur Ildusovich, author
  • Soloveva Valeriya Vladimirovna, author
  • Khaybullina Svetlana Francevna, author
  • Bibliographic description in the original language Solovyeva V.V. Human Adipose Derived Stem Cells Do Not Alter Cytokine Secretion in Response To The Genetic Modification With pEGFP-N2 Plasmid DNA / V.V. Solovyeva, I.I. Salafutdinov, E.V. Martynova, S.F. Khaiboullina, A.A. Rizvanov // World Applied Sciences Journal. – 2013. – Vol.26, No.7. – P.968-972.
    Annotation Adipose tissue contain progenitor cells with regenerative (angiogenic, neuroprotection, trophic etc.) potential and treatment based on adipose tissue-derived stem cells (ADSCs) transplantation may constitute a promising therapy. Genetic modification of stem cells with genes encoding growth factors and other biologically active molecules might further increase therapeutic efficiency. However, there is a question about the advantages and disadvantages of such gene/stem cell therapy. For a better understanding of the mechanisms occurring in organism after cell transplantation we should first study cell behavior in vitro. Here we report results of ADSCs transfection with plasmid DNA pEGFP-N2 and subsequent study of cytokines and chemokines secretion using Luminex technology.
    Keywords Plasmid, pEGFP-N2, Cytokines, Chemokines, Human Adipose Derived Stem Cells, Transfection
    The name of the journal World Applied Sciences Journal
    URL http://www.idosi.org/wasj/wasj26%287%2913/21.pdf
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=94046&p_lang=2

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