KFU. Card publication. Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

EVALUATION OF CELL MEMBRANE-MODULATING PROPERTIES OF NON-IONIC SURFACTANTS WITH THE USE OF ATOMIC FORCE SPECTROSCOPY

Form of presentation

Articles in international journals and collections

Year of publication

2014

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Authors, employees of KFU

Osin Yuriy Nikolaevich, author

Bibliographic description in the original language

Oksana V. Bondar, Denis V. Lebedev, Vesta D. Shevchenko, Anastas A. Bukharaev, Yury N. Osin, Yurii G. Shtyrlin, Timur I. Abdullin Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy // BioNanoSceince, -2014

Annotation

Analytical possibilities of atomic force spectroscopy (AFS) in liquid were studied upon interaction of membranotropic polymers with the plasma membrane of human cells. Topographical visualization of tightly adherent dermal fibroblasts, but not relatively soft prostate cancer (PC-3) cells, was achieved using a conventional triangular cantilever. A microsphere-based probe has been developed and applied for AFS analysis of micromechanical properties of PC-3 cells. Non-ionic block copolymers of ethylene oxide and propylene oxide, bi-functional Pluronic? L61 and glycerol-based tri-functional copolymer (TFC), were studied as potential modulators of cellular membranes and drug delivery systems [1]. As indicated by dynamic light scattering and fluorescent techniques, Pluronic? L61 and TFC were adsorbed onto the cell surface and inserted into the plasma membrane in different extent.

Keywords

cellular membranes; elastic properties; cancer cells; atomic force spectroscopy; non-ionic surfactants; block copolymers of ethylene oxide and propylene oxide; membrane-modulating properties; microviscosity; nanocarriers

The name of the journal

BioNanoScience

URL

http://link.springer.com/journal/12668

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=93874&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Osin Yuriy Nikolaevich	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	�ksana V. Bondar, Denis V. Lebedev, Vesta D. Shevchenko, Anastas A. Bukharaev, Yury N. Osin, Yurii G. Shtyrlin, Timur I. Abdullin Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy // BioNanoSceince, -2014	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=93874&p_lang=2	ru_RU
dc.description.abstract	BioNanoScience	ru_RU
dc.description.abstract	Analytical possibilities of atomic force spectroscopy (AFS) in liquid were studied upon interaction of membranotropic polymers with the plasma membrane of human cells. Topographical visualization of tightly adherent dermal fibroblasts, but not relatively soft prostate cancer (PC-3) cells, was achieved using a conventional triangular cantilever. A microsphere-based probe has been developed and applied for AFS analysis of micromechanical properties of PC-3 cells. Non-ionic block copolymers of ethylene oxide and propylene oxide, bi-functional Pluronic? L61 and glycerol-based tri-functional copolymer (TFC), were studied as potential modulators of cellular membranes and drug delivery systems [1]. As indicated by dynamic light scattering and fluorescent techniques, Pluronic? L61 and TFC were adsorbed onto the cell surface and inserted into the plasma membrane in different extent.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Evaluation of Cell Membrane-Modulating Properties of Non-Ionic Surfactants With the Use of Atomic Force Spectroscopy	ru_RU
dc.type	Articles in international journals and collections	ru_RU