KFU. Card publication. Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge

KAZAN
FEDERAL UNIVERSITY

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COMPARATIVE GENOME SEQUENCING REVEALS GENOMIC SIGNATURE OF EXTREME DESICCATION TOLERANCE IN THE ANHYDROBIOTIC MIDGE

Form of presentation

Articles in Russian journals and collections

Year of publication

2014

Authors, employees of KFU

Gusev Oleg Aleksandrovich, author

Other authors

Oleg Gusev, Yoshitaka Suetsugu, Richard Cornette, Takeshi Kawashima, Maria D. Logacheva, Alexey S. Kondrashov, Aleksey A. Penin, Rie Hatanaka, Shingo Kikuta, Sachiko Shimura, Hiroyuki Kanamori, Yuichi Katayose, Takashi Matsumoto, Elena Shagimardanova, Dmitry Alexeev, Vadim Govorun, Jennifer Wisecaver, Alexander Mikheyev, Ryo Koyanagi, Manabu Fujie, Tomoaki Nishiyama, Shuji Shigenobu, Tomoko F. Shibata, Veronika Golygina, Mitsuyasu Hasebe, Takashi Okuda, Nori Satoh & Takahiro Kikawada

Bibliographic description in the original language

Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge

Annotation

Anhydrobiosis represents an extreme example of tolerance adaptation to water loss, where an organism can survive in an ametabolic state until water returns. Here we report the first comparative analysis examining the genomic background of extreme desiccation tolerance, which is exclusively found in larvae of the only anhydrobiotic insect, Polypedilum vanderplanki. We compare the genomes of P. vanderplanki and a congeneric desiccation-sensitive midge P. nubifer. We determine that the genome of the anhydrobiotic species specifically contains clusters of multi-copy genes with products that act as molecular shields. In addition, the genome possesses several groups of genes with high similarity to known protective proteins. However, these genes are located in distinct paralogous clusters in the genome apart from the classical orthologues of the corresponding genes shared by both chironomids and other insects. The transcripts of these clustered paralogues contribute to a large majority of

Keywords

anhydrobiosis, chironomids, desiccation

The name of the journal

Nature Communications

URL

http://www.nature.com/ncomms/2014/140912/ncomms5784/full/ncomms5784.html

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=91826&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gusev Oleg Aleksandrovich	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=91826&p_lang=2	ru_RU
dc.description.abstract	Nature Communications	ru_RU
dc.description.abstract	Anhydrobiosis represents an extreme example of tolerance adaptation to water loss, where an organism can survive in an ametabolic state until water returns. Here we report the first comparative analysis examining the genomic background of extreme desiccation tolerance, which is exclusively found in larvae of the only anhydrobiotic insect, Polypedilum vanderplanki. We compare the genomes of P. vanderplanki and a congeneric desiccation-sensitive midge P. nubifer. We determine that the genome of the anhydrobiotic species specifically contains clusters of multi-copy genes with products that act as molecular shields. In addition, the genome possesses several groups of genes with high similarity to known protective proteins. However, these genes are located in distinct paralogous clusters in the genome apart from the classical orthologues of the corresponding genes shared by both chironomids and other insects. The transcripts of these clustered paralogues contribute to a large majority of	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	anhydrobiosis	ru_RU
dc.subject	chironomids	ru_RU
dc.subject	desiccation	ru_RU
dc.title	Comparative genome sequencing reveals genomic signature of extreme desiccation tolerance in the anhydrobiotic midge	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU