KFU. Card publication. Morpholes neurons compromise the development of cortical connectivity

KAZAN
FEDERAL UNIVERSITY

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MORPHOLES NEURONS COMPROMISE THE DEVELOPMENT OF CORTICAL CONNECTIVITY

Form of presentation

Articles in international journals and collections

Year of publication

2009

Authors, employees of KFU

Gafarov Fail Mubarakovich, author

Khusnutdinov Nail Rustamovich, author

Other authors

Galimyanov, F.

Bibliographic description in the original language

Gafarov, F. , Khusnutdinov, N., Galimyanov, F. Morpholes neurons compromise the development of cortical connectivity. Journal of Integrative Neuroscience Volume 8, Issue 1, 2009, Pages 35-48

Annotation

It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcircuits lead to changes of activity, i.e., changes in information encoded. Specific patterns of external stimulation can lead to creation of new synaptic connections between neurons. The calcium influxes controlled by neuronal activity regulate the processes of neurotrophic factors released by neurons, growth cones movement and synapse differentiation in developing neural systems. We propose a model for description and investigation of the activity dependent development of neural networks. The dynamics of the network parameters (activity, diffusion of axon guidance chemicals, growth cone position) is described by a closed set of differential equations. The model presented here describes the development of neural networks under the assumption of activity dependent axon guidance molecules. Numerical simulation show

Keywords

Axon guidance; Network growth; Structural plasticity

The name of the journal

Journal of Integrative Neuroscience

URL

http://www.worldscientific.com/doi/abs/10.1142/S0219635209002058

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=89247&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gafarov Fail Mubarakovich	ru_RU
dc.contributor.author	Khusnutdinov Nail Rustamovich	ru_RU
dc.date.accessioned	2009-01-01T00:00:00Z	ru_RU
dc.date.available	2009-01-01T00:00:00Z	ru_RU
dc.date.issued	2009	ru_RU
dc.identifier.citation	Gafarov, F. , Khusnutdinov, N., Galimyanov, F. Morpholes neurons compromise the development of cortical connectivity. Journal of Integrative Neuroscience Volume 8, Issue 1, 2009, Pages 35-48	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=89247&p_lang=2	ru_RU
dc.description.abstract	Journal of Integrative Neuroscience	ru_RU
dc.description.abstract	It is currently accepted that cortical maps are dynamic constructions that are altered in response to external input. Experience-dependent structural changes in cortical microcircuits lead to changes of activity, i.e., changes in information encoded. Specific patterns of external stimulation can lead to creation of new synaptic connections between neurons. The calcium influxes controlled by neuronal activity regulate the processes of neurotrophic factors released by neurons, growth cones movement and synapse differentiation in developing neural systems. We propose a model for description and investigation of the activity dependent development of neural networks. The dynamics of the network parameters (activity, diffusion of axon guidance chemicals, growth cone position) is described by a closed set of differential equations. The model presented here describes the development of neural networks under the assumption of activity dependent axon guidance molecules. Numerical simulation show	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Morpholes neurons compromise the development of cortical connectivity	ru_RU
dc.type	Articles in international journals and collections	ru_RU