KFU. Card publication. Coulometric analysis of medicines and raw medicinal plant materials

KAZAN
FEDERAL UNIVERSITY

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- 中文
- ES

COULOMETRIC ANALYSIS OF MEDICINES AND RAW MEDICINAL PLANT MATERIALS

Form of presentation

Articles in Russian journals and collections

Year of publication

2014

Authors, employees of KFU

Budnikov German Konstantinovich, author

Ziyatdinova Guzel Kamilevna, author

Bibliographic description in the original language

Abdullina S.G. Coulometric analysis of medicines and raw medicinal plant materials / S.G. Abdullina, O.A. Lira, N.M. Agapova, I.K. Petrova, G.K. Ziyatdinova, G.K. Budnikov, I.P. Rudakova, N.V. Pyatigorkaya, I.A. Samylina // Farmatsiya. - 2014. - No. 3. - P. 3-5.

Annotation

A constant current coulometric titration method was proposed for controlling the quality of pharmaceutical substances, raw medicinal plant materials (RMPM), and their based preparations. The method advantages associated with the possible automation of measurements, the absence of stages of titrant standardization and calibration graph construction were considered. The sum of organic acids in RMPM was estimated from their reactions with electrogenerated hydroxide ions in water, by using potassium sulfate as an electrolyte and by testing the validity of titration by the reference titer ?Hydrochloric Acid?. Bromine was electrochemically generated from potassium bromide in 0.M sulfuric acid; iodine from potassium iodide in hydrogen chloride buffer solution, and hypoiodite ions from potassium iodide in phosphate buffer solution at pH 9.8, by testing the validity of titration by the reference titer ?Sodium hyposulfite 5-hydrate?. Electrogenerated iodine was proposed for the determination of the content of ascorbic acid in the rosehip preparations and hypoiodite ions for that of tannins in RMPM. The electrogenerated hydroxide ions and bromine were used for assay of pharmaceutical substances.

Keywords

constant current coulometric titration, electrogenerated hydroxide halogens, pharmaceuticals, raw medicinal plant material, assay

The name of the journal

Фармация

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=84000&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Budnikov German Konstantinovich	ru_RU
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	Abdullina S.G. Coulometric analysis of medicines and raw medicinal plant materials / S.G. Abdullina, O.A. Lira, N.M. Agapova, I.K. Petrova, G.K. Ziyatdinova, G.K. Budnikov, I.P. Rudakova, N.V. Pyatigorkaya, I.A. Samylina // Farmatsiya. - 2014. - No. 3. - P. 3-5.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=84000&p_lang=2	ru_RU
dc.description.abstract	Фармация	ru_RU
dc.description.abstract	A constant current coulometric titration method was proposed for controlling the quality of pharmaceutical substances, raw medicinal plant materials (RMPM), and their based preparations. The method advantages associated with the possible automation of measurements, the absence of stages of titrant standardization and calibration graph construction were considered. The sum of organic acids in RMPM was estimated from their reactions with electrogenerated hydroxide ions in water, by using potassium sulfate as an electrolyte and by testing the validity of titration by the reference titer ?Hydrochloric Acid?. Bromine was electrochemically generated from potassium bromide in 0.M sulfuric acid; iodine from potassium iodide in hydrogen chloride buffer solution, and hypoiodite ions from potassium iodide in phosphate buffer solution at pH 9.8, by testing the validity of titration by the reference titer ?Sodium hyposulfite 5-hydrate?. Electrogenerated iodine was proposed for the determination of the content of ascorbic acid in the rosehip preparations and hypoiodite ions for that of tannins in RMPM. The electrogenerated hydroxide ions and bromine were used for assay of pharmaceutical substances.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	constant current coulometric titration	ru_RU
dc.subject	electrogenerated hydroxide halogens	ru_RU
dc.subject	pharmaceuticals	ru_RU
dc.subject	raw medicinal plant material	ru_RU
dc.subject	assay	ru_RU
dc.title	Coulometric analysis of medicines and raw medicinal plant materials	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU