KFU. Card publication. Synthesis and Antimicrobial Activitiy of Bis-4,6-Sulfonamidated 5,7- Dinitrobenzofuroxans

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SYNTHESIS AND ANTIMICROBIAL ACTIVITIY OF BIS-4,6-SULFONAMIDATED 5,7- DINITROBENZOFUROXANS

Form of presentation

Articles in international journals and collections

Year of publication

2014

Authors, employees of KFU

Bakhtiyarova Yuliya Valerevna, author

Galkin Vladimir Ivanovich, author

Galkina Irina Vasilevna, author

Tudriy Elena Vadimovna, author

Other authors

Luiza Usupova; Marina Shulaeva; Oskar Pozdeev; Svetlana Egorova

Bibliographic description in the original language

Irina Galkina, Elena Tudriy, Yuliya Bakhtiyarova, Luiza Usupova, Marina Shulaeva, Oskar Pozdeev, Svetlana Egorova, Vladimir Galkin. Synthesis and Antimicrobial Activitiy of Bis-4,6-Sulfonamidated 5,7- Dinitrobenzofuroxans / Journal of Chemistry, vol.2014,Article ID 367351, 6 pages, 2014. doi:10.1155/2014/367351

Annotation

A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7-11 has been synthesized and tested for antimicrobial activity. The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy and mass spectrometry (MALDITOF). The synthesized compounds were tested for their in vitro antimicrobial activity using the disk diffusion method against Gram-positive bacteria Staphylococcus aureus, the Gram-negative bacteria Escherichia �oli, Pseudomonas aeruginosa and Proteus mirabilis, the fungal strain Aspergillus niger and the yeast-like pathogenic fungus Candida albicans. Our results indicate that the compounds 7-11 exhibit potent antimicrobial activity. The stability of the compounds was evaluated by TG and DSC-methods.

Keywords

bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans, antimicrobial activity, Gram-positive bacteria, Gram-negative bacteria, pathogenic fungus

The name of the journal

Journal of Chemistry

URL

http://www.hindawi.com/journals/jchem/2014/367351

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=80732&p_lang=2

Resource files

File name	Size (MB)	Format
367351_round_1.pdf	0,22	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Bakhtiyarova Yuliya Valerevna	ru_RU
dc.contributor.author	Galkin Vladimir Ivanovich	ru_RU
dc.contributor.author	Galkina Irina Vasilevna	ru_RU
dc.contributor.author	Tudriy Elena Vadimovna	ru_RU
dc.date.accessioned	2014-01-01T00:00:00Z	ru_RU
dc.date.available	2014-01-01T00:00:00Z	ru_RU
dc.date.issued	2014	ru_RU
dc.identifier.citation	Irina Galkina, Elena Tudriy, Yuliya Bakhtiyarova, Luiza Usupova, Marina Shulaeva, Oskar Pozdeev, Svetlana Egorova, Vladimir Galkin. Synthesis and Antimicrobial Activitiy of Bis-4,6-Sulfonamidated 5,7- Dinitrobenzofuroxans / Journal of Chemistry, vol.2014,Article ID 367351, 6 pages, 2014. doi:10.1155/2014/367351	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=80732&p_lang=2	ru_RU
dc.description.abstract	Journal of Chemistry	ru_RU
dc.description.abstract	A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7-11 has been synthesized and tested for antimicrobial activity. The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy and mass spectrometry (MALDITOF). The synthesized compounds were tested for their in vitro antimicrobial activity using the disk diffusion method against Gram-positive bacteria Staphylococcus aureus, the Gram-negative bacteria Escherichia �oli, Pseudomonas aeruginosa and Proteus mirabilis, the fungal strain Aspergillus niger and the yeast-like pathogenic fungus Candida albicans. Our results indicate that the compounds 7-11 exhibit potent antimicrobial activity. The stability of the compounds was evaluated by TG and DSC-methods.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	bis-4	ru_RU
dc.subject	6-sulfonamidated 5	ru_RU
dc.subject	7-dinitrbenzofuroxans	ru_RU
dc.subject	antimicrobial activity	ru_RU
dc.subject	Gram-positive bacteria	ru_RU
dc.subject	Gram-negative bacteria	ru_RU
dc.subject	pathogenic fungus	ru_RU
dc.title	Synthesis and Antimicrobial Activitiy of Bis-4,6-Sulfonamidated 5,7- Dinitrobenzofuroxans	ru_RU
dc.type	Articles in international journals and collections	ru_RU