Form of presentation | Articles in international journals and collections |
Year of publication | 2013 |
Язык | русский |
|
Blatt Nataliya Lvovna, author
Lombardi Vinsent Klifford , author
Mingaleeva Rimma Niyazovna, author
Rizvanov Albert Anatolevich, author
Soloveva Valeriya Vladimirovna, author
Khaybullina Svetlana Francevna, author
|
Bibliographic description in the original language |
Blatt N.L. Application of Cell and Tissue Culture Systems for Anticancer Drug Screening / N.L. Blatt, R.N. Mingaleeva, V.V. Solovieva, S.F. Khaiboullina, V.C. Lombardi, A.A. Rizvanov // World Applied Sciences Journal. – 2013. – Vol.23, No.3. – P.315-325. |
Annotation |
World Applied Sciences Journal |
Keywords |
Cancer, Tumor, Drug Screening, Chemotherapeutics Running title Anti-Cancer Drug Screening Systems |
The name of the journal |
World Applied Sciences Journal
|
URL |
http://www.idosi.org/wasj/wasj23%283%2913/5.pdf |
Please use this ID to quote from or refer to the card |
https://repository.kpfu.ru/eng/?p_id=66651&p_lang=2 |
Full metadata record |
Field DC |
Value |
Language |
dc.contributor.author |
Blatt Nataliya Lvovna |
ru_RU |
dc.contributor.author |
Lombardi Vinsent Klifford |
ru_RU |
dc.contributor.author |
Mingaleeva Rimma Niyazovna |
ru_RU |
dc.contributor.author |
Rizvanov Albert Anatolevich |
ru_RU |
dc.contributor.author |
Soloveva Valeriya Vladimirovna |
ru_RU |
dc.contributor.author |
Khaybullina Svetlana Francevna |
ru_RU |
dc.date.accessioned |
2013-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2013-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2013 |
ru_RU |
dc.identifier.citation |
Blatt N.L. Application of Cell and Tissue Culture Systems for Anticancer Drug Screening / N.L. Blatt, R.N. Mingaleeva, V.V. Solovieva, S.F. Khaiboullina, V.C. Lombardi, A.A. Rizvanov // World Applied Sciences Journal. – 2013. – Vol.23, No.3. – P.315-325. |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/eng/?p_id=66651&p_lang=2 |
ru_RU |
dc.description.abstract |
World Applied Sciences Journal |
ru_RU |
dc.description.abstract |
World Applied Sciences Journal |
ru_RU |
dc.description.abstract |
A primary reason why potential anticancer drugs fail in clinical trials is the limitations of existing in vitro screening systems. The purpose of in vitro testing is to aid in the selection of efficacious compounds from a range of candidates with variable levels of the desired properties.
In vitro cell-culture tumor models are the most widely used screening systems, however, they lack the complexity of the natural microenvironment of the host organism. Clearly, an effective screening system should possess qualities and organization similar to those of a natural tumor microenvironment. In an attempt to better simulate a tumor and its microenvironment sophisticated models have been developed, such as the three-dimensional cultures. In addition to these in vitro culture methods, tissue-based testing methods have been used to screen potential anticancer drugs but these methods have limited utility. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
Cancer |
ru_RU |
dc.subject |
Tumor |
ru_RU |
dc.subject |
Drug Screening |
ru_RU |
dc.subject |
Chemotherapeutics Running title Anti-Cancer Drug Screening Systems |
ru_RU |
dc.title |
Application of Cell and Tissue Culture Systems for Anticancer Drug Screening |
ru_RU |
dc.type |
Articles in international journals and collections |
ru_RU |
|