KFU. Card publication. Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment

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CHARACTERIZATION OF THE SECRETOME OF HUMAN TOOTH GERM STEM CELLS (HTGSCS) REVEALS NEURO-PROTECTION BY FINE-TUNING MICRO-ENVIRONMENT

Form of presentation

Articles in international journals and collections

Year of publication

2013

Authors, employees of KFU

Rizvanov Albert Anatolevich, author

Other authors

M.E. Yalvac; A. Yarat; D. Mercan; A. Palotas; F. Sahin

Bibliographic description in the original language

Yalvac M.E. Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment / M.E. Yalvac, A. Yarat, D. Mercan, A.A. Rizvanov, A. Palotas, F. Sahin // Brain, Behavior, and Immunity. – 2013. – Vol.32. – P.122-130

Annotation

Bone-marrow-derived mesenchymal stem cells (MSCs) demonstrate neuro-protective effects in several disease models. By producing growth-factors, cytokines and chemokines, they promote survival of neurons in damaged brain areas. Alternative MSC sources, such as human tooth germ stem cells (hTGSCs), have been investigated for their neuro-protective properties. They ameliorate effects of neuro-toxic agents by paracrine mechanisms, however these secreted bio-active molecules are not yet characterized. Therefore, the current study aimed to provide a detailed analysis of the secretome of hTGSCs.

Keywords

Bio-active molecules, Cytokine, Human tooth germ stem cells (hTGSCs), Neuro-protection, Secretome, Toxicity

The name of the journal

BRAIN BEHAV IMMUN

URL

http://www.sciencedirect.com/science/article/pii/S0889159113001360

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=66643&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Rizvanov Albert Anatolevich	ru_RU
dc.date.accessioned	2013-01-01T00:00:00Z	ru_RU
dc.date.available	2013-01-01T00:00:00Z	ru_RU
dc.date.issued	2013	ru_RU
dc.identifier.citation	Yalvac M.E. Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment / M.E. Yalvac, A. Yarat, D. Mercan, A.A. Rizvanov, A. Palotas, F. Sahin // Brain, Behavior, and Immunity. – 2013. – Vol.32. – P.122-130	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=66643&p_lang=2	ru_RU
dc.description.abstract	BRAIN BEHAV IMMUN	ru_RU
dc.description.abstract	Bone-marrow-derived mesenchymal stem cells (MSCs) demonstrate neuro-protective effects in several disease models. By producing growth-factors, cytokines and chemokines, they promote survival of neurons in damaged brain areas. Alternative MSC sources, such as human tooth germ stem cells (hTGSCs), have been investigated for their neuro-protective properties. They ameliorate effects of neuro-toxic agents by paracrine mechanisms, however these secreted bio-active molecules are not yet characterized. Therefore, the current study aimed to provide a detailed analysis of the secretome of hTGSCs.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Bio-active molecules	ru_RU
dc.subject	Cytokine	ru_RU
dc.subject	Human tooth germ stem cells (hTGSCs)	ru_RU
dc.subject	Neuro-protection	ru_RU
dc.subject	Secretome	ru_RU
dc.subject	Toxicity	ru_RU
dc.title	Characterization of the secretome of human tooth germ stem cells (hTGSCs) reveals neuro-protection by fine-tuning micro-environment	ru_RU
dc.type	Articles in international journals and collections	ru_RU