KFU. Card publication. Fusion thermodynamics of native cyclodextrins

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

FUSION THERMODYNAMICS OF NATIVE CYCLODEXTRINS

Form of presentation

Articles in international journals and collections

Year of publication

2025

Язык

английский

Authors, employees of KFU

Gatiatulin Askar Kamilevich, author

Gorbachuk Valeriy Vilenovich, author

Ziganshin Marat Akhmedovich, author

Bibliographic description in the original language

Gatiatulin A.K., Gabdulkhaev M.N., Tagirov S.R., Fusion thermodynamics of native cyclodextrins//Thermochimica Acta. - 2025. - Vol.753, Is.. - Art. №180115.

Annotation

The fusion thermodynamics of native cyclodextrins was studied, which provides a basis for modelling their behavior in various applications. The fusion enthalpies and entropies of high-temperature polymorphs of α-cyclodextrin and β-cyclodextrin were determined using fast scanning calorimetry with a heating rate up to 40,000 K s–1. A high-temperature polymorph of anhydrous α-cyclodextrin (polymorph III) was obtained and for the first time characterized using powder X-ray diffraction and thermal analysis. The comparison of experimental fusion enthalpies of native cyclodextrins with the data of theoretical additive-constitutive model shows a good agreement for β-cyclodextrin and previously studied γ-cyclodextrin. The experimental data on fusion entropy were used to estimate the flexibility of cyclodextrin molecules in liquid state. The flexibility of β-cyclodextrin and γ-cyclodextrin is close to the theoretical values for corresponding non-macrocyclic oligosaccharides, while as α-cyclodextrin molecule remains rigid in liquid phase. This is a factor in favor of the higher α-cyclodextrin affinity for guests that can be accommodated in its cavity.

Keywords

Cyclodextrin, Fast scanning calorimetry, Polymorphism, Fusion enthalpy, Fusion entropy

The name of the journal

THERMOCHIMICA ACTA

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-105014515535&doi=10.1016%2Fj.tca.2025.180115&partnerID=40&md5=fee5d4f67729fcbae1b3c7379f9bc2af

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=318945&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gatiatulin Askar Kamilevich	ru_RU
dc.contributor.author	Gorbachuk Valeriy Vilenovich	ru_RU
dc.contributor.author	Ziganshin Marat Akhmedovich	ru_RU
dc.date.accessioned	2025-01-01T00:00:00Z	ru_RU
dc.date.available	2025-01-01T00:00:00Z	ru_RU
dc.date.issued	2025	ru_RU
dc.identifier.citation	Gatiatulin A.K., Gabdulkhaev M.N., Tagirov S.R., Fusion thermodynamics of native cyclodextrins//Thermochimica Acta. - 2025. - Vol.753, Is.. - Art. №180115.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=318945&p_lang=2	ru_RU
dc.description.abstract	THERMOCHIMICA ACTA	ru_RU
dc.description.abstract	The fusion thermodynamics of native cyclodextrins was studied, which provides a basis for modelling their behavior in various applications. The fusion enthalpies and entropies of high-temperature polymorphs of α-cyclodextrin and β-cyclodextrin were determined using fast scanning calorimetry with a heating rate up to 40,000 K s–1. A high-temperature polymorph of anhydrous α-cyclodextrin (polymorph III) was obtained and for the first time characterized using powder X-ray diffraction and thermal analysis. The comparison of experimental fusion enthalpies of native cyclodextrins with the data of theoretical additive-constitutive model shows a good agreement for β-cyclodextrin and previously studied γ-cyclodextrin. The experimental data on fusion entropy were used to estimate the flexibility of cyclodextrin molecules in liquid state. The flexibility of β-cyclodextrin and γ-cyclodextrin is close to the theoretical values for corresponding non-macrocyclic oligosaccharides, while as α-cyclodextrin molecule remains rigid in liquid phase. This is a factor in favor of the higher α-cyclodextrin affinity for guests that can be accommodated in its cavity.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Cyclodextrin	ru_RU
dc.subject	Fast scanning calorimetry	ru_RU
dc.subject	Polymorphism	ru_RU
dc.subject	Fusion enthalpy	ru_RU
dc.subject	Fusion entropy	ru_RU
dc.title	Fusion thermodynamics of native cyclodextrins	ru_RU
dc.type	Articles in international journals and collections	ru_RU