KFU. Card publication. Population, physiological, and genetic insights into carbendazim resistence in populations of the phytopathogenic fungus Microdochium nivale

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POPULATION, PHYSIOLOGICAL, AND GENETIC INSIGHTS INTO CARBENDAZIM RESISTENCE IN POPULATIONS OF THE PHYTOPATHOGENIC FUNGUS MICRODOCHIUM NIVALE

Form of presentation

Articles in international journals and collections

Year of publication

2025

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Authors, employees of KFU

Ponomareva Mira Leonidovna, author

Bibliographic description in the original language

Murzagulova G.Sh., Gogoleva O.A., Ryazanov E.A., Shatravina K.A., Tendiuk N.V., Sakhabutdinov I.T., Ponomarev S.N., Chastukhina I.B., Makshakova O.N., Ponomareva M.L., Gorshkov V.Y. Population, physiological, and genetic insights into carbendazim resistence in populations of the phytopathogenic fungus Microdochium nivale // J. Fungi. 2025. V. 11. I. 9. p. 639.

Annotation

Fungicide treatment is one of the most common methods for controlling fungal plant diseases. However, many phytopathogenic fungi develop resistance to fungicides. Addressing this agriculturally important issue requires comprehensive investigations into fungicide resistance. Our study aims to assess the degree and prevalence of resistance to carbendazim—one of the most widely used fungicides—in populations of Microdochium nivale, the causal agent of the deleterious plant disease pink snow mold; to explore possible relationships between carbendazim resistance and physiological and genetic traits; and to gain insight into the molecular basis of carbendazim resistance in this species. We showed that carbendazim resistance is widespread in the analyzed M. nivale populations, and that the application of carbendazim increases the proportion of resistant strains. Nevertheless, carbendazim-resistant strains are present at high relative abundance in populations that have never been exposed to fungicides. Carbendazim resistance in M. nivale is strongly associated with sequence variations in the β-tubulin gene, resulting in amino acid sequence variability that leads to differential affinity for carbendazim. Additionally, we propose a metabarcoding-based approach employing a genetic marker linked to a specific phenotypic trait to assess the ratio of genotypes with contrasting properties within a particular fungal species in environmental communities.

Keywords

fungicide resistance; intrapopulation heterogeneity of phytopathogenic fungi; Microdochium nivale; winter cereal crops; virulence; plant infectious diseases

The name of the journal

Journal Fungi

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=316792&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ponomareva Mira Leonidovna	ru_RU
dc.date.accessioned	2025-01-01T00:00:00Z	ru_RU
dc.date.available	2025-01-01T00:00:00Z	ru_RU
dc.date.issued	2025	ru_RU
dc.identifier.citation	Murzagulova G.Sh., Gogoleva O.A., Ryazanov E.A., Shatravina K.A., Tendiuk N.V., Sakhabutdinov I.T., Ponomarev S.N., Chastukhina I.B., Makshakova O.N., Ponomareva M.L., Gorshkov V.Y. Population, physiological, and genetic insights into carbendazim resistence in populations of the phytopathogenic fungus Microdochium nivale // J. Fungi. 2025. V. 11. I. 9. p. 639.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=316792&p_lang=2	ru_RU
dc.description.abstract	Journal Fungi	ru_RU
dc.description.abstract	Fungicide treatment is one of the most common methods for controlling fungal plant diseases. However, many phytopathogenic fungi develop resistance to fungicides. Addressing this agriculturally important issue requires comprehensive investigations into fungicide resistance. Our study aims to assess the degree and prevalence of resistance to carbendazim—one of the most widely used fungicides—in populations of Microdochium nivale, the causal agent of the deleterious plant disease pink snow mold; to explore possible relationships between carbendazim resistance and physiological and genetic traits; and to gain insight into the molecular basis of carbendazim resistance in this species. We showed that carbendazim resistance is widespread in the analyzed M. nivale populations, and that the application of carbendazim increases the proportion of resistant strains. Nevertheless, carbendazim-resistant strains are present at high relative abundance in populations that have never been exposed to fungicides. Carbendazim resistance in M. nivale is strongly associated with sequence variations in the β-tubulin gene, resulting in amino acid sequence variability that leads to differential affinity for carbendazim. Additionally, we propose a metabarcoding-based approach employing a genetic marker linked to a specific phenotypic trait to assess the ratio of genotypes with contrasting properties within a particular fungal species in environmental communities.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Population, physiological, and genetic insights into carbendazim resistence in populations of the phytopathogenic fungus Microdochium nivale	ru_RU
dc.type	Articles in international journals and collections	ru_RU