KFU. Card publication. Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults

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TWO-YEAR STUDY ON THE INTRA-INDIVIDUAL DYNAMICS OF GUT MICROBIOTA AND SHORT-CHAIN FATTY ACIDS PROFILES IN HEALTHY ADULTS

Form of presentation

Articles in international journals and collections

Year of publication

2024

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Authors, employees of KFU

Bulygina Evgeniya Aleksandrovna, author

Grigoreva Tatyana Vladimirovna, author

Kayumov Ayrat Rashitovich, author

Kupriyanova Olga Vsevolodovna, author

Markelova Mariya Ivanovna, author

Senina Anastasiya Mikhaylovna, author

Sinyagina Mariya Nikolaevna, author

Synbulatova Gulnaz Emilevna, author

Khusnutdinova Dilyara Rashidovna, author

Bibliographic description in the original language

Senina A. Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults / A. Senina, M. Markelova, D. Khusnutdinova, M. Siniagina, O. Kupriyanova, G. Synbulatova, A. Kayumov, E. Boulygina, T. Grigoryeva // Microorganisms. – 2024. – T. 12. – �. 8. – S. 1712.

Annotation

Microorganisms

Keywords

gut microbiota; 16S rRNA; short chain fatty acids (SCFAs); healthy microbiota; temporal stability; seasonal changes; individual fingerprint

The name of the journal

Microorganisms

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=312220&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Bulygina Evgeniya Aleksandrovna	ru_RU
dc.contributor.author	Grigoreva Tatyana Vladimirovna	ru_RU
dc.contributor.author	Kayumov Ayrat Rashitovich	ru_RU
dc.contributor.author	Kupriyanova Olga Vsevolodovna	ru_RU
dc.contributor.author	Markelova Mariya Ivanovna	ru_RU
dc.contributor.author	Senina Anastasiya Mikhaylovna	ru_RU
dc.contributor.author	Sinyagina Mariya Nikolaevna	ru_RU
dc.contributor.author	Synbulatova Gulnaz Emilevna	ru_RU
dc.contributor.author	Khusnutdinova Dilyara Rashidovna	ru_RU
dc.date.accessioned	2024-01-01T00:00:00Z	ru_RU
dc.date.available	2024-01-01T00:00:00Z	ru_RU
dc.date.issued	2024	ru_RU
dc.identifier.citation	Senina A. Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults / A. Senina, M. Markelova, D. Khusnutdinova, M. Siniagina, O. Kupriyanova, G. Synbulatova, A. Kayumov, E. Boulygina, T. Grigoryeva // Microorganisms. – 2024. – �. 12. – �. 8. – �. 1712.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=312220&p_lang=2	ru_RU
dc.description.abstract	Microorganisms	ru_RU
dc.description.abstract	While the gut microbiome has been intensively investigated for more than twenty years already, its role in various disorders remains to be unraveled. At the same time, questions about what changes in the gut microbiota can be considered as normal or pathological and whether communities are able to recover after exposure to negative factors (diseases, medications, environmental factors) are still unclear. Here, we describe changes in the gut microbiota composition and the content of short-chain fatty acids in adult healthy volunteers (n = 15) over a 24 month-period. Intraindividual variability in gut microbial composition was 40%, whereas the short chain fatty acids profile remained relatively stable (2-year variability 20%, inter-individual 26%). The changes tend to accumulate over time. Nevertheless, both short-term and long-term changes in the gut microbiome composition were significantly smaller within individuals than interindividual differences (two-year interindividual variability was 75%). Seasonal changes in gut microbiota were found more often in autumn and spring involving the content of minor representatives (less than 1.5% of the community in average) in the phyla Actinobacteriota, Firmicutes and Proteobacteria.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults	ru_RU
dc.type	Articles in international journals and collections	ru_RU