KFU. Card publication. ULTRASOUND-MEDIATED GENERATION OF MEMBRANE VESICLES FROM HUMAN CELLS

KAZAN
FEDERAL UNIVERSITY

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ULTRASOUND-MEDIATED GENERATION OF MEMBRANE VESICLES FROM HUMAN CELLS

Form of presentation

Articles in Russian journals and collections

Year of publication

2025

Authors, employees of KFU

Gomzikova Marina Olegovna, author

Kvon Anna Igorevna, author

Syromyatnikova Valeriya Yurevna, author

Bibliographic description in the original language

Zhurnal opublikuetsya tolko v aprele

Annotation

Extracellular vesicles (EVs) are membrane particles of cellular origin that play a major role in intercellular communication. EVs have a number of characteristics that make them promising agents for targeted delivery of drugs and biologically active factors. However, their use in clinical practice is limited due to the lack of an industrially adapted production method that provides a high yield of vesicles while maintaining their biological activity. The aim of this article is to analyze of the morphology, size and cytoplasmic content of ultrasound (US)-generated membrane vesicles (MVs) from producer cells. MVs were generated by US treatment of producer cells. The concentration and size of the resulting vesicles were analyzed by NTA (nanoparticle tracking analysis) and SEM (scanning electron microscopy). We also assessed whether US-MVs contain the cytoplasmic content of the parental cell or whether there is a loss of cytosolic content upon rupture of the cell membrane. To do this,...

Keywords

extracellular vesicles; membrane vesicles, ultrasound-induced vesicles; mesenchymal stem cells; multipotent stromal cells; delivery system

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=311569&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gomzikova Marina Olegovna	ru_RU
dc.contributor.author	Kvon Anna Igorevna	ru_RU
dc.contributor.author	Syromyatnikova Valeriya Yurevna	ru_RU
dc.date.accessioned	2025-01-01T00:00:00Z	ru_RU
dc.date.available	2025-01-01T00:00:00Z	ru_RU
dc.date.issued	2025	ru_RU
dc.identifier.citation	Журнал опубликуется только в апреле	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=311569&p_lang=2	ru_RU
dc.description.abstract	Extracellular vesicles (EVs) are membrane particles of cellular origin that play a major role in intercellular communication. EVs have a number of characteristics that make them promising agents for targeted delivery of drugs and biologically active factors. However, their use in clinical practice is limited due to the lack of an industrially adapted production method that provides a high yield of vesicles while maintaining their biological activity. The aim of this article is to analyze of the morphology, size and cytoplasmic content of ultrasound (US)-generated membrane vesicles (MVs) from producer cells. MVs were generated by US treatment of producer cells. The concentration and size of the resulting vesicles were analyzed by NTA (nanoparticle tracking analysis) and SEM (scanning electron microscopy). We also assessed whether US-MVs contain the cytoplasmic content of the parental cell or whether there is a loss of cytosolic content upon rupture of the cell membrane. To do this,...	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	extracellular vesicles; membrane vesicles	ru_RU
dc.subject	ultrasound-induced vesicles; mesenchymal stem cells; multipotent stromal cells; delivery system	ru_RU
dc.title	ULTRASOUND-MEDIATED GENERATION OF MEMBRANE VESICLES FROM HUMAN CELLS	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU