KFU. Card publication. Red Blood Cell Aggregation within a Blood Clot Causes Clot Shrinkage

KAZAN
FEDERAL UNIVERSITY

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RED BLOOD CELL AGGREGATION WITHIN A BLOOD CLOT CAUSES CLOT SHRINKAGE

Form of presentation

Conference proceedings in international journals and collections

Year of publication

2024

Язык

английский

Authors, employees of KFU

Khismatullin Rafael Rafikovich, author

Bibliographic description in the original language

Program: Oral and Poster Abstracts Session: 101. Red Cells and Erythropoiesis, Excluding Iron: Poster II Hematology Disease Topics & Pathways: Research, Fundamental Science, Translational Research, Diseases, Biological Processes, Pathogenesis

Annotation

ASH 2024 meeting

Keywords

contraction, retraction, RBCs, platelets, aggregation

The name of the journal

ASH 2024 meeting

URL

https://ash.confex.com/ash/2024/webprogram/Paper208535.html

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=306589&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Khismatullin Rafael Rafikovich	ru_RU
dc.date.accessioned	2024-01-01T00:00:00Z	ru_RU
dc.date.available	2024-01-01T00:00:00Z	ru_RU
dc.date.issued	2024	ru_RU
dc.identifier.citation	Program: Oral and Poster Abstracts Session: 101. Red Cells and Erythropoiesis, Excluding Iron: Poster II Hematology Disease Topics & Pathways: Research, Fundamental Science, Translational Research, Diseases, Biological Processes, Pathogenesis	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=306589&p_lang=2	ru_RU
dc.description.abstract	ASH 2024 meeting	ru_RU
dc.description.abstract	Volumetric shrinkage of blood clots known as clot contraction (retraction) driven by the activated platelets is important for hemostasis and thrombosis. RBCs make up more than a half of the volume of a blood clot, but their possible contribution to clot contraction is unknown, especially in severe thrombocytopenia and/or thrombocytopathies. Remarkably, in whole blood, unlike in platelet-rich plasma, platelet inhibitors never suppress clot contraction completely, suggesting a residual active mechanical contribution from RBCs. This study aims at elucidating the ability of RBCs per se to promote clot shrinkage and explore the underlying mechanisms.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	contraction	ru_RU
dc.subject	retraction	ru_RU
dc.subject	RBCs	ru_RU
dc.subject	platelets	ru_RU
dc.subject	aggregation	ru_RU
dc.title	Red Blood Cell Aggregation within a Blood Clot Causes Clot Shrinkage	ru_RU
dc.type	Conference proceedings in international journals and collections	ru_RU