KFU. Card publication. Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease

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FUNCTIONAL ACTIVITY OF BLOOD NEUTROPHILS IN PATIENTS WITH STABLE COURSE AND EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Form of presentation

Articles in international journals and collections

Year of publication

2023

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Authors, employees of KFU

Kubysheva Nailya Iskhakovna, author

Other authors

Eliseeva Tatyana , author

Karaulov Alexandr , author

Khrapunova Ekaterina , author

Novikov Viktor , author

Ovsyannikov Dmitry , author

Postnikova Larisa , author

Soodaeva Svetlana , author

Stroganov Andrey , author

Bibliographic description in the original language

Kubysheva N.I., Postnikova L.B., Novikov V.V., Soodaeva S.K., Eliseeva T.I., Khrapunova E.I., Stroganov A.B., Ovsyannikov D.Yu., Karaulov A.V.. Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease. Bull Exp Biol Med, 176, 26–29 (2023).

Annotation

A comparative study of the parameters of chemiluminescence (CL) of blood neutrophils in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD) in different periods of the disease was carried out. The maximum values of induced and spontaneous CL were recorded at moderate severity of the disease during exacerbation. Low levels of CL indicators were found in severe COPD in stable phase. The values of the induction period of the chemiluminescent response in patients with moderate COPD were higher compared with the control group. Correlations between the values of induced chemiluminescence of neutrophils and the indicator of respiration function FEV1 were established, which may indicate the influence of multidirectional changes in the functional activity of systemic neutrophils on the development and worsening of airway obstruction in COPD patients.

Keywords

COPD; chemiluminescence; neutrophils

The name of the journal

Bulletin of Experimental Biology and Medicine

URL

https://link.springer.com/article/10.1007/s10517-023-05960-6

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=293459&p_lang=2

Resource files

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Functional_activity_of_blood_neutrophils_in_stable_course_and_exacerbation_in_patients_with_COPD.pdf	0,35	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kubysheva Nailya Iskhakovna	ru_RU
dc.contributor.author	Eliseeva Tatyana	ru_RU
dc.contributor.author	Karaulov Alexandr	ru_RU
dc.contributor.author	Khrapunova Ekaterina	ru_RU
dc.contributor.author	Novikov Viktor	ru_RU
dc.contributor.author	Ovsyannikov Dmitry	ru_RU
dc.contributor.author	Postnikova Larisa	ru_RU
dc.contributor.author	Soodaeva Svetlana	ru_RU
dc.contributor.author	Stroganov Andrey	ru_RU
dc.date.accessioned	2023-01-01T00:00:00Z	ru_RU
dc.date.available	2023-01-01T00:00:00Z	ru_RU
dc.date.issued	2023	ru_RU
dc.identifier.citation	Kubysheva N.I., Postnikova L.B., Novikov V.V., Soodaeva S.K., Eliseeva T.I., Khrapunova E.I., Stroganov A.B., Ovsyannikov D.Yu., Karaulov A.V.. Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease. Bull Exp Biol Med, 176, 26–29 (2023).	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=293459&p_lang=2	ru_RU
dc.description.abstract	Bulletin of Experimental Biology and Medicine	ru_RU
dc.description.abstract	A comparative study of the parameters of chemiluminescence (CL) of blood neutrophils in patients with varying degrees of severity of chronic obstructive pulmonary disease (COPD) in different periods of the disease was carried out. The maximum values of induced and spontaneous CL were recorded at moderate severity of the disease during exacerbation. Low levels of CL indicators were found in severe COPD in stable phase. The values of the induction period of the chemiluminescent response in patients with moderate COPD were higher compared with the control group. Correlations between the values of induced chemiluminescence of neutrophils and the indicator of respiration function FEV1 were established, which may indicate the influence of multidirectional changes in the functional activity of systemic neutrophils on the development and worsening of airway obstruction in COPD patients.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease	ru_RU
dc.type	Articles in international journals and collections	ru_RU