KFU. Card publication. Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury

KAZAN
FEDERAL UNIVERSITY

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INVESTIGATION OF NO ROLE IN NEURAL TISSUE IN BRAIN AND SPINAL CORD INJURY

Form of presentation

Articles in international journals and collections

Year of publication

2023

Язык

английский

Authors, employees of KFU

Andrianov Vyacheslav Vadimovich, author

Bogodvid Tatyana Khalilovna, author

Gaynutdinov Khalil Latypovich, author

Deryabina Irina Borisovna, author

Muranova Lyudmila Nikolaevna, author

Silanteva Dinara Irekovna, author

Bibliographic description in the original language

Andrianov, V.V.; Kulchitsky, V.A.; Yafarova, G.G.; Bazan, L.V.; Bogodvid, T.K.; Deryabina, I.B.; Muranova, L.N.; Silantyeva, D.I.; Arslanov, A.I.; Paveliev, M.N.; et al. Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury. Molecules 2023, 28, 7359. https://doi.org/10.3390/molecules28217359

Annotation

Nitric oxide (NO) production in injured and intact brain regions was compared by EPR spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of the brain was injured, followed by the spinal cord at the level of the first lumbar vertebra. Seven days after brain injury, a reduction in NO content of 84% in injured brain regions and 66% in intact brain regions was found. The difference in NO production in injured and uninjured brain regions persisted 7 days after injury. The copper content in the brain remained unchanged one week after modeling of brain and spinal cord injury. The data obtained in the experiments help to explain the problems in the therapy of patients with combined brain injury.

Keywords

nitric oxide; cooper; brain stroke; spinal cord injury; electron paramagnetic resonance

The name of the journal

Molecules

URL

https://www.mdpi.com/1420-3049/28/21/7359

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=290704&p_lang=2

Resource files

File name	Size (MB)	Format
F_molecules_28_07359.pdf	2,36	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Andrianov Vyacheslav Vadimovich	ru_RU
dc.contributor.author	Bogodvid Tatyana Khalilovna	ru_RU
dc.contributor.author	Gaynutdinov Khalil Latypovich	ru_RU
dc.contributor.author	Deryabina Irina Borisovna	ru_RU
dc.contributor.author	Muranova Lyudmila Nikolaevna	ru_RU
dc.contributor.author	Silanteva Dinara Irekovna	ru_RU
dc.date.accessioned	2023-01-01T00:00:00Z	ru_RU
dc.date.available	2023-01-01T00:00:00Z	ru_RU
dc.date.issued	2023	ru_RU
dc.identifier.citation	Andrianov, V.V.; Kulchitsky, V.A.; Yafarova, G.G.; Bazan, L.V.; Bogodvid, T.K.; Deryabina, I.B.; Muranova, L.N.; Silantyeva, D.I.; Arslanov, A.I.; Paveliev, M.N.; et al. Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury. Molecules 2023, 28, 7359. https://doi.org/10.3390/molecules28217359	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=290704&p_lang=2	ru_RU
dc.description.abstract	Molecules	ru_RU
dc.description.abstract	Nitric oxide (NO) production in injured and intact brain regions was compared by EPR spectroscopy in a model of brain and spinal cord injury in Wistar rats. The precentral gyrus of the brain was injured, followed by the spinal cord at the level of the first lumbar vertebra. Seven days after brain injury, a reduction in NO content of 84% in injured brain regions and 66% in intact brain regions was found. The difference in NO production in injured and uninjured brain regions persisted 7 days after injury. The copper content in the brain remained unchanged one week after modeling of brain and spinal cord injury. The data obtained in the experiments help to explain the problems in the therapy of patients with combined brain injury.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Investigation of NO Role in Neural Tissue in Brain and Spinal Cord Injury	ru_RU
dc.type	Articles in international journals and collections	ru_RU