KFU. Card publication. Langendorff-Isolated Rat Heart after Acute Åxperimental Myocardial Infarction

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FEDERAL UNIVERSITY

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LANGENDORFF-ISOLATED RAT HEART AFTER ACUTE ÅXPERIMENTAL MYOCARDIAL INFARCTION

Form of presentation

Articles in Russian journals and collections

Year of publication

2022

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Authors, employees of KFU

Zefirov Timur Lvovich, author

Ziyatdinova Nafisa Ilgizovna, author

Kupcova Anna Mikhaylovna, author

Authors, postgraduates KFU

Bugrov Roman Kutdusovich, postgraduate kfu

Bibliographic description in the original language

Kuptsova A.M. Langendorff-Isolated Rat Heart after Acute Experimental Myocardial Infarction / A.M. Kuptsova, R.K. Bugrov, N.I. Ziyatdinova, and T.L. Zefrov // Vulletin of Experimental Biology and Medicine, Vol. 173, ¹6, - 2022. rr. 719-722

Annotation

A comparative analysis of functioning of Langendorff-isolated heart from intact rats, sham-operated rats, and rats with a model of myocardial infarction one day after ligation of the left coronary artery was carried out. No signifcant differences in inotropic and chronotropic functions of the heart were found in the groups of intact and sham-operated animals. In the group of rats with the myocardial infarction model, an increase in HR and a decrease in the maximum contraction and relaxation rates and left-ventricular developed pressure were shown in comparison with the groups of intact and sham-operated animals. At the same time, in the group of sham-operated animals, a decrease in coronary fow and temporal parameters of contraction was observed.

Keywords

myocardial infarction model; isolated heart; rat

The name of the journal

Áþëëåòåíü ýêñïåðèìåíòàëüíîé áèîëîãèè è ìåäèöèíû

URL

https://link.springer.com/article/10.1007/s10517-022-05623-y

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=289994&p_lang=2

Resource files

File name	Size (MB)	Format
BEBiM_2022_Langendorff_Isolated_Rat__eart_after_Acute_Experimental_Myocardial_Infarction.pdf	0,41	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Zefirov Timur Lvovich	ru_RU
dc.contributor.author	Ziyatdinova Nafisa Ilgizovna	ru_RU
dc.contributor.author	Kupcova Anna Mikhaylovna	ru_RU
dc.contributor.author	Bugrov Roman Kutdusovich	ru_RU
dc.date.accessioned	2022-01-01T00:00:00Z	ru_RU
dc.date.available	2022-01-01T00:00:00Z	ru_RU
dc.date.issued	2022	ru_RU
dc.identifier.citation	Kuptsova A.M. Langendorff-Isolated Rat Heart after Acute Åxperimental Myocardial Infarction / A.M. Kuptsova, R.K. Bugrov, N.I. Ziyatdinova, and T.L. Zefrov // Âulletin of Experimental Biology and Medicine, Vol. 173, ¹6, - 2022. ðð. 719-722	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=289994&p_lang=2	ru_RU
dc.description.abstract	Áþëëåòåíü ýêñïåðèìåíòàëüíîé áèîëîãèè è ìåäèöèíû	ru_RU
dc.description.abstract	A comparative analysis of functioning of Langendorff-isolated heart from intact rats, sham-operated rats, and rats with a model of myocardial infarction one day after ligation of the left coronary artery was carried out. No signifcant differences in inotropic and chronotropic functions of the heart were found in the groups of intact and sham-operated animals. In the group of rats with the myocardial infarction model, an increase in HR and a decrease in the maximum contraction and relaxation rates and left-ventricular developed pressure were shown in comparison with the groups of intact and sham-operated animals. At the same time, in the group of sham-operated animals, a decrease in coronary fow and temporal parameters of contraction was observed.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Langendorff-Isolated Rat Heart after Acute Åxperimental Myocardial Infarction	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU