KFU. Card publication. Artificial microvesicles: new perspective on healing tendon wounds

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

ARTIFICIAL MICROVESICLES: NEW PERSPECTIVE ON HEALING TENDON WOUNDS

Form of presentation

Russian monographs

Year of publication

2022

Язык

андийский

Authors, employees of KFU

Aymaletdinov Aleksandr Maazovich, author

Bibliographic description in the original language

Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health and welfare. Advances in cell therapies have started to overcome some of these issues, however complications such as the formation of ectopic bone remain a complication of this technique. Regenerative medicine is therefore looking towards future therapies such as the introduction of microvesicles (MVs) derived from stem cells (SCs). The aim of the present study was to assess the characteristics of artificially derived MVs, from equine mesenchymal stem cells (MSCs), when delivered to rat tendon cells in vitro and damaged tendons in vivo. The initial stages of extracting MVs from equine MSCs and identifying and characterising the cultured tendon stem/progenitor cells (TSCs) from rat Achilles

Keywords

Tendon, Stem/progenitor cell, Microvesicle, Differentiation, Membrane fusion

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=284796&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Aymaletdinov Aleksandr Maazovich	ru_RU
dc.date.accessioned	2022-01-01T00:00:00Z	ru_RU
dc.date.available	2022-01-01T00:00:00Z	ru_RU
dc.date.issued	2022	ru_RU
dc.identifier.citation	Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health and welfare. Advances in cell therapies have started to overcome some of these issues, however complications such as the formation of ectopic bone remain a complication of this technique. Regenerative medicine is therefore looking towards future therapies such as the introduction of microvesicles (MVs) derived from stem cells (SCs). The aim of the present study was to assess the characteristics of artificially derived MVs, from equine mesenchymal stem cells (MSCs), when delivered to rat tendon cells in vitro and damaged tendons in vivo. The initial stages of extracting MVs from equine MSCs and identifying and characterising the cultured tendon stem/progenitor cells (TSCs) from rat Achilles	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=284796&p_lang=2	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Tendon	ru_RU
dc.subject	Stem/progenitor cell	ru_RU
dc.subject	Microvesicle	ru_RU
dc.subject	Differentiation	ru_RU
dc.subject	Membrane fusion	ru_RU
dc.title	Artificial microvesicles: new perspective on healing tendon wounds	ru_RU
dc.type	Russian monographs	ru_RU