KFU. Card publication. A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery

KAZAN
FEDERAL UNIVERSITY

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A GLUCOSE‐RESPONSIVE POLYMER NANOCARRIER BASED ON SULFONATED RESORCINARENE FOR CONTROLLED INSULIN DELIVERY

Form of presentation

Articles in international journals and collections

Year of publication

2019

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Authors, employees of KFU

Ziganshina Albina Yulduzovna, author

Bibliographic description in the original language

T. Yu. Sergeeva, R. K. Mukhitova, I. R. Nizameev, M. K. Kadirov, A. S. Sapunova, A. D. Voloshina, T. A. Mukhametzyanov, A. Y. Ziganshina, I. S. Antipin / A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery // ChemPlusChem. – 2019. – 84. – 1560-1566.

Annotation

An insulin nanocarrier was synthesized by the microemulsion polymerization of sulfonated resorcinarenes with phenylboronic acid. The nanocarrier is stable at normal glucose levels, and it dissociates at a glucose concentration about 10 mM. The insulin encapsulation and release were investigated by NMR, UV, and fluorescence spectroscopy. An increase in glucose concentration from 5 to 10 mM leads to an increase in the insulin release from 10 to 100 %.

Keywords

nanovarrier, insulin, glucose

The name of the journal

ChemPlusChem

URL

https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cplu.201900428

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=262888&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ziganshina Albina Yulduzovna	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	T. Yu. Sergeeva, R. K. Mukhitova, I. R. Nizameev, M. K. Kadirov, A. S. Sapunova, A. D. Voloshina, T. A. Mukhametzyanov, A. Y. Ziganshina, I. S. Antipin / A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery // ChemPlusChem. – 2019. – 84. – 1560-1566.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=262888&p_lang=2	ru_RU
dc.description.abstract	ChemPlusChem	ru_RU
dc.description.abstract	An insulin nanocarrier was synthesized by the microemulsion polymerization of sulfonated resorcinarenes with phenylboronic acid. The nanocarrier is stable at normal glucose levels, and it dissociates at a glucose concentration about 10 mM. The insulin encapsulation and release were investigated by NMR, UV, and fluorescence spectroscopy. An increase in glucose concentration from 5 to 10 mM leads to an increase in the insulin release from 10 to 100 %.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	nanovarrier	ru_RU
dc.subject	insulin	ru_RU
dc.subject	glucose	ru_RU
dc.title	A Glucose‐Responsive Polymer Nanocarrier Based on Sulfonated Resorcinarene for Controlled Insulin Delivery	ru_RU
dc.type	Articles in international journals and collections	ru_RU