Form of presentation | Articles in international journals and collections |
Year of publication | 2021 |
Язык | английский |
|
Pavelev Roman Sergeevich, author
|
Bibliographic description in the original language |
Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040. |
Annotation |
In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient. |
Keywords |
pyridoxine, vitamin B6, antiseptic |
The name of the journal |
AIP Conference Proceedings
|
URL |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120410305&doi=10.1063%2f5.0068420&partnerID=40&md5=d35907ab35f3080ef4a200cb123f35d2 |
Please use this ID to quote from or refer to the card |
https://repository.kpfu.ru/eng/?p_id=261926&p_lang=2 |
Full metadata record ![](https://shelly.kpfu.ru/pdf/picture/arrow_black_right.gif) |
Field DC |
Value |
Language |
dc.contributor.author |
Pavelev Roman Sergeevich |
ru_RU |
dc.date.accessioned |
2021-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2021-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2021 |
ru_RU |
dc.identifier.citation |
Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040. |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/eng/?p_id=261926&p_lang=2 |
ru_RU |
dc.description.abstract |
AIP Conference Proceedings |
ru_RU |
dc.description.abstract |
In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
pyridoxine |
ru_RU |
dc.subject |
vitamin B6 |
ru_RU |
dc.subject |
antiseptic |
ru_RU |
dc.title |
Synthetic route optimization of pyridosept antiseptic drug candidate |
ru_RU |
dc.type |
Articles in international journals and collections |
ru_RU |
|