KFU. Card publication. Synthetic route optimization of pyridosept antiseptic drug candidate

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

SYNTHETIC ROUTE OPTIMIZATION OF PYRIDOSEPT ANTISEPTIC DRUG CANDIDATE

Form of presentation

Articles in international journals and collections

Year of publication

2021

Язык

английский

Authors, employees of KFU

Pavelev Roman Sergeevich, author

Bibliographic description in the original language

Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040.

Annotation

In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient.

Keywords

pyridoxine, vitamin B6, antiseptic

The name of the journal

AIP Conference Proceedings

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120410305&doi=10.1063%2f5.0068420&partnerID=40&md5=d35907ab35f3080ef4a200cb123f35d2

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=261926&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Pavelev Roman Sergeevich	ru_RU
dc.date.accessioned	2021-01-01T00:00:00Z	ru_RU
dc.date.available	2021-01-01T00:00:00Z	ru_RU
dc.date.issued	2021	ru_RU
dc.identifier.citation	Sapozhnikov S.V, Pavelyev R.S, Shtyrlin N.V, Synthetic route optimization of pyridosept antiseptic drug candidate//AIP Conference Proceedings. - 2021. - Vol.2388, Is.. - Art. №030040.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=261926&p_lang=2	ru_RU
dc.description.abstract	AIP Conference Proceedings	ru_RU
dc.description.abstract	In this work we have described the transformation of synthetic route of the antiseptic drug candidate Pyridosept. Initial method has included in seven steps and has poor overall yield of target compound. This is the convenient developing process, scalable and technologi. The overall yield was increased up to 22% in four steps without column chromatography purification which allows to obtain the target compound with purity of 99.5+% which is especially important for the active ingredient.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	pyridoxine	ru_RU
dc.subject	vitamin B6	ru_RU
dc.subject	antiseptic	ru_RU
dc.title	Synthetic route optimization of pyridosept antiseptic drug candidate	ru_RU
dc.type	Articles in international journals and collections	ru_RU