KFU. Card publication. Experimental study of ultrastructural mechanisms and kinetics of tegumental secretion in cestodes parasiting fish (Cestoda: Diphyllobothriidea)

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EXPERIMENTAL STUDY OF ULTRASTRUCTURAL MECHANISMS AND KINETICS OF TEGUMENTAL SECRETION IN CESTODES PARASITING FISH (CESTODA: DIPHYLLOBOTHRIIDEA)

Form of presentation

Articles in international journals and collections

Year of publication

2021

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Authors, employees of KFU

Biserova Natalya Mikhaylovna, author

Bibliographic description in the original language

Kutyrev I.A., Biserova N.M., Mazur O.E., Dugarov Zh.N. Experimental study of ultrastructural mechanisms and kinetics of tegumental secretion in cestodes parasiting fish (Cestoda: Diphyllobothriidea) Journal of Fish Diseases. 2021.V 44. Is 8 DOI: 10.1111/jfd.13386

Annotation

The structural response and plasticity of the cestode tegument in response to the influence of the host organism is not yet well understood. The main aims of our in vitro study were to analyse the ultrastructural mechanisms and kinetics of tegumental secretion in two cestodes species, Dibothriocephalus dendriticus and Ligula interrupta in response to the influence of fish host blood serum. The incubation of plerocercoids in the culture medium, which contained fish host blood serum, resulted in an increased number of secretory products on the tegument surface. Our study is the first to experimentally demonstrate the formation of plerocercoid protective layers influenced by the host's internal environment factors. The mechanism of the generation of the protective layer included the following: the intensive formation of organelles in the tegumental cytons and their transfer to the distal cytoplasm of the tegument; increases in extracellular vesicles and vacuoles released on the tegument surface; arrangement of secretory products and fine-dispersed extracellular matrix in layers and formation of the protective layer. The structural tegumental response included increases in the glycocalyx layer and structural changes. Our study revealed that the universal mechanism of protective layer formation was intrinsic to different tapeworms. Hypothetically, plerocercoids of cestodes parasiting in fish may use tegumental secretion for the formation of a protective layer and for the release of immunoregulator molecules to evade of the host's immune response.

Keywords

apocrine and merocrine secretion, excretory/secretory products, extracellular matrix, glycocalyx, tapeworms, tegument.

The name of the journal

Journal of Fish Diseases

URL

https://onlinelibrary.wiley.com/doi/abs/10.1111/jfd.13386

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=258143&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Biserova Natalya Mikhaylovna	ru_RU
dc.date.accessioned	2021-01-01T00:00:00Z	ru_RU
dc.date.available	2021-01-01T00:00:00Z	ru_RU
dc.date.issued	2021	ru_RU
dc.identifier.citation	Kutyrev I.A., Biserova N.M., Mazur O.E., Dugarov Zh.N. Experimental study of ultrastructural mechanisms and kinetics of tegumental secretion in cestodes parasiting fish (Cestoda: Diphyllobothriidea) Journal of Fish Diseases. 2021.V 44. Is 8 DOI: 10.1111/jfd.13386	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=258143&p_lang=2	ru_RU
dc.description.abstract	Journal of Fish Diseases	ru_RU
dc.description.abstract	The structural response and plasticity of the cestode tegument in response to the influence of the host organism is not yet well understood. The main aims of our in vitro study were to analyse the ultrastructural mechanisms and kinetics of tegumental secretion in two cestodes species, Dibothriocephalus dendriticus and Ligula interrupta in response to the influence of fish host blood serum. The incubation of plerocercoids in the culture medium, which contained fish host blood serum, resulted in an increased number of secretory products on the tegument surface. Our study is the first to experimentally demonstrate the formation of plerocercoid protective layers influenced by the host's internal environment factors. The mechanism of the generation of the protective layer included the following: the intensive formation of organelles in the tegumental cytons and their transfer to the distal cytoplasm of the tegument; increases in extracellular vesicles and vacuoles released on the tegument surface; arrangement of secretory products and fine-dispersed extracellular matrix in layers and formation of the protective layer. The structural tegumental response included increases in the glycocalyx layer and structural changes. Our study revealed that the universal mechanism of protective layer formation was intrinsic to different tapeworms. Hypothetically, plerocercoids of cestodes parasiting in fish may use tegumental secretion for the formation of a protective layer and for the release of immunoregulator molecules to evade of the host's immune response.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	apocrine and merocrine secretion	ru_RU
dc.subject	excretory/secretory products	ru_RU
dc.subject	extracellular matrix	ru_RU
dc.subject	glycocalyx	ru_RU
dc.subject	tapeworms	ru_RU
dc.subject	tegument.	ru_RU
dc.title	Experimental study of ultrastructural mechanisms and kinetics of tegumental secretion in cestodes parasiting fish (Cestoda: Diphyllobothriidea)	ru_RU
dc.type	Articles in international journals and collections	ru_RU