KFU. Card publication. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers

- RUS
- 中文
- ES

INTERPOLYELECTROLYTE MIXED NANOPARTICLES FROM ANIONIC AND CATIONIC THIACALIX[4]ARENES FOR SELECTIVE RECOGNITION OF MODEL BIOPOLYMERS

Form of presentation

Articles in international journals and collections

Year of publication

2019

��

��

Authors, employees of KFU

Kunafina Aysylu Favisovna, author

Nugmanova Aygul Rafilevna, author

Osin Yuriy Nikolaevich, author

Padnya Pavel Leonidovich, author

Stoykov Ivan Ivanovich, author

Yakimova Lyudmila Sergeevna, author

Bibliographic description in the original language

Yakimova, L. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers / L. Yakimova, P. Padnya, D. Tereshina, A. Nugmanova, A. Kunafina, Y. Osin, V. Evtugyn, I. Stoikov // Journal of Molecular Liquids. – 2019. – V. 279. – P. 9–17.

Annotation

In this paper, we propose and develop an approach to synthesize an interpolyelectrolyte mixed nanoparticles of cationic and anionic thiacalix[4]arene derivatives, capable to selective recognition of model biopolymers (DNA from calf thymus, lysozyme, bovine serum albumin). Some ammonium and sulfonate derivatives of the p-tert-butylthiacalix[4]arene were chosen as supramolecular building blocks of these nanoparticles. In addition, we synthesized sulfobetaine-functionalized macrocycle where anionic and cationic groups are included in one molecular platform. Depending on conformation of macrocyclic platform (cone, 1,3-alternate) interpolyelectrolyte mixed nanoparticles with different size, stability and morphology were synthesized. We showed that the recognition of biopolymers is selective and depends on the ability to forming of nano-associates and the nature (charge) of the functional groups on the surface of the interpolyelectrolyte mixed nanoparticles. Negatively charged interpolyelectrolyte mixed nanoparticles form associates with lysozyme, while positively charged interpolyelectrolytes compact the high molecular DNA from calf thymus. The sulfobetaine derivatives of the thiacalix[4]arene stabilize monomeric form of BSA. ? 2019 Elsevier B.V.

Keywords

Interpolyelectrolyte, nanoparticles, thiacalix[4]arenes, biopolymers

The name of the journal

Journal of Molecular Liquids

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=246059&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kunafina Aysylu Favisovna	ru_RU
dc.contributor.author	Nugmanova Aygul Rafilevna	ru_RU
dc.contributor.author	Osin Yuriy Nikolaevich	ru_RU
dc.contributor.author	Padnya Pavel Leonidovich	ru_RU
dc.contributor.author	Stoykov Ivan Ivanovich	ru_RU
dc.contributor.author	Yakimova Lyudmila Sergeevna	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Yakimova, L. Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers / L. Yakimova, P. Padnya, D. Tereshina, A. Nugmanova, A. Kunafina, Y. Osin, V. Evtugyn, I. Stoikov // Journal of Molecular Liquids. – 2019. – V. 279. – P. 9–17.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=246059&p_lang=2	ru_RU
dc.description.abstract	Journal of Molecular Liquids	ru_RU
dc.description.abstract	In this paper, we propose and develop an approach to synthesize an interpolyelectrolyte mixed nanoparticles of cationic and anionic thiacalix[4]arene derivatives, capable to selective recognition of model biopolymers (DNA from calf thymus, lysozyme, bovine serum albumin). Some ammonium and sulfonate derivatives of the p-tert-butylthiacalix[4]arene were chosen as supramolecular building blocks of these nanoparticles. In addition, we synthesized sulfobetaine-functionalized macrocycle where anionic and cationic groups are included in one molecular platform. Depending on conformation of macrocyclic platform (cone, 1,3-alternate) interpolyelectrolyte mixed nanoparticles with different size, stability and morphology were synthesized. We showed that the recognition of biopolymers is selective and depends on the ability to forming of nano-associates and the nature (charge) of the functional groups on the surface of the interpolyelectrolyte mixed nanoparticles. Negatively charged interpolyelectrolyte mixed nanoparticles form associates with lysozyme, while positively charged interpolyelectrolytes compact the high molecular DNA from calf thymus. The sulfobetaine derivatives of the thiacalix[4]arene stabilize monomeric form of BSA. ? 2019 Elsevier B.V.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Interpolyelectrolyte	ru_RU
dc.subject	nanoparticles	ru_RU
dc.subject	thiacalix[4]arenes	ru_RU
dc.subject	biopolymers	ru_RU
dc.title	Interpolyelectrolyte mixed nanoparticles from anionic and cationic thiacalix[4]arenes for selective recognition of model biopolymers	ru_RU
dc.type	Articles in international journals and collections	ru_RU