KFU. Card publication. Dynamics of free radical indicators of exhaled breath condensate in smokers.

KAZAN
FEDERAL UNIVERSITY

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DYNAMICS OF FREE RADICAL INDICATORS OF EXHALED BREATH CONDENSATE IN SMOKERS.

Form of presentation

Conference proceedings in international journals and collections

Year of publication

2019

Язык

английский

Authors, employees of KFU

Kubysheva Nailya Iskhakovna, author

Other authors

Glukhova M. , author

Klimanov Igor , author

Li Timur , author

Murakaeva L. , author

Popova Nataliia , author

Smirnov M. , author

Soodaeva Svetlana , author

Zaprudnova E. , author

Bibliographic description in the original language

Soodaeva, S. K., Zaprudnova, E. A., Smirnov, M. V., Klimanov, I. A., Li, T. V., Popova, N. A., MurakaevaL.R., Glukhova M.V., Kubysheva, N. I. (2019). Dynamics of free radical indicators of exhaled breath condensate in smokers. European Respiratory Journal 2019; 54: Suppl. 63, PA4103.

Annotation

European Respiratory Journal 2019; 54: Suppl. 63.

Keywords

Nitric oxide, smoking, COPD - mechanism

The name of the journal

European Respiratory Journal 2019; 54: Suppl. 63.

URL

https://erj.ersjournals.com/content/54/suppl_63/PA4103.abstract

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=244544&p_lang=2

Resource files

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F_Dynamics_of_free_radical_indicators_of_exhaled_breath_condensate_in_smokers.pdf	0,32	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kubysheva Nailya Iskhakovna	ru_RU
dc.contributor.author	Glukhova M.	ru_RU
dc.contributor.author	Klimanov Igor	ru_RU
dc.contributor.author	Li Timur	ru_RU
dc.contributor.author	Murakaeva L.	ru_RU
dc.contributor.author	Popova Nataliia	ru_RU
dc.contributor.author	Smirnov M.	ru_RU
dc.contributor.author	Soodaeva Svetlana	ru_RU
dc.contributor.author	Zaprudnova E.	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Soodaeva, S. K., Zaprudnova, E. A., Smirnov, M. V., Klimanov, I. A., Li, T. V., Popova, N. A., MurakaevaL.R., Glukhova M.V., Kubysheva, N. I. (2019). Dynamics of free radical indicators of exhaled breath condensate in smokers. European Respiratory Journal 2019; 54: Suppl. 63, PA4103.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=244544&p_lang=2	ru_RU
dc.description.abstract	European Respiratory Journal 2019; 54: Suppl. 63.	ru_RU
dc.description.abstract	Objective: to study the indicators of free radical status in exhaled breath condensate (ESC): the level of total concentration of nitrates and nitrites(NO2-/NO3-), malonic dialdehyde (MDA) and iron concentrations in young smokers without diagnosed diseases of the respiratory system and older smokers with COPD II during the stable phase. The study involved young smokers aged 15–23 years with smoking experience of 1 and more years, smokers aged 37–69 years, suffering from COPD II for three or more years. The control group consisted of non-smokers from 20 to 35 years old, without diagnosed diseases of the respiratory system. It was found that in young people, smoking leads to a decrease in the concentration of NO2-/NO3- in EBC by 4.2 times compared with the control (P <0.05). Patients with COPD II showed an increase in the NO2-/NO3- by 2.16 times (P <0.05). The consequence of the activation of free radical oxidation is increased lipid peroxidation, detected by the formation of MDA. In patients with COPD II, the level of MDA increases and exceeds the level of non-smokers by 3.16 times (P <0.05). However, in young smokers, there were no significant differences in the level of MDA compared with non-smokers, although an upward trend was observed. The activation of free radical processes is also evidenced by the observed increase in the level of Fe2 + in the EBC in both young smokers and smokers with COPD II. In young smokers, a violation of free radical metabolism is observed. In smokers with COPD, an escalation of the activation of free radical processes was observed, accompanied by an increase in lipid peroxidation, an increase in the level of Fe2 + and NO2-/NO3- in EBC.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Nitric oxide	ru_RU
dc.subject	smoking	ru_RU
dc.subject	COPD - mechanism	ru_RU
dc.title	Dynamics of free radical indicators of exhaled breath condensate in smokers.	ru_RU
dc.type	Conference proceedings in international journals and collections	ru_RU