KFU. Card publication. Novel modified electrode with immobilized galvinoxyl radical for the voltammetric determination of antioxidant activity

KAZAN
FEDERAL UNIVERSITY

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NOVEL MODIFIED ELECTRODE WITH IMMOBILIZED GALVINOXYL RADICAL FOR THE VOLTAMMETRIC DETERMINATION OF ANTIOXIDANT ACTIVITY

Form of presentation

Articles in international journals and collections

Year of publication

2020

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Authors, employees of KFU

Budnikov German Konstantinovich, author

Ziyatdinova Guzel Kamilevna, author

Authors, students KFU

Snegureva Yuliya Vladimirovna, author

Bibliographic description in the original language

Ziyatdinova, G. Novel modified electrode with immobilized galvinoxyl radical for the voltammetric determination of antioxidant activity / G. Ziyatdinova, Yu. Zelenova, H. Budnikov // J. Electroanal. Chem. – 2020. – V. 586. - Art. � 113677. - 7 p.

Annotation

Galvinoxyl radical (GO) immobilized on the electrode surface has been used for the voltammetric determination of antioxidant activity for the first time. Immobilization of radical on glassy carbon electrode (GCE) provides improvement of the system reversibility as well as increase of the redox currents in comparison to GO reduction in solution. But sensitivity of response is insufficient for the antioxidant activity estimation. Application of GCE modified with dispersion of CeO2 nanoparticles (NP) in cationic surfactant cetylpyridinium bromide (CPB) medium (CeO2 NP-CPB/GCE) as a base for GO immobilization provide full reversibility of its reduction (redox currents ratio of 1.02 and peak potential separation of 80 mV) and 7-fold increase of the redox currents at physiological pH of supporting electrolyte. Electrode developed has been successfully applied for the voltammetric evaluation of natural phenolics antioxidant activity expressed as the EC50 parameter (effective concentration of the antioxidant providing 50% inhibition of GO) and antioxidant activity of herbal preparations (tinctures, infusions and decoctions) as relative GO inhibition. Antioxidant activity of natural phenolics is decreased as morin > quercetin = ferulic acid > gallic acid > tannin ≈ catechin. The results obtained agree well with data of standard spectrophotometric method. The advantages of the method developed are 4-fold lower incubation time, less consumption of the reagents and the absence of limitations for colored samples.

Keywords

Cyclic voltammetry, chemically modified electrodes, galvinoxyl radical, cerium dioxide nanoparticles, antioxidant activity, phytochemical analysis

The name of the journal

Journal of Electroanalytical Chemistry

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076009922&doi=10.1016%2fj.jelechem.2019.113677&partnerID=40&md5=2a50ed89c0d99c79cf0fa6a431608357

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=227935&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Budnikov German Konstantinovich	ru_RU
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.contributor.author	Snegureva Yuliya Vladimirovna	ru_RU
dc.date.accessioned	2020-01-01T00:00:00Z	ru_RU
dc.date.available	2020-01-01T00:00:00Z	ru_RU
dc.date.issued	2020	ru_RU
dc.identifier.citation	Ziyatdinova, G. Novel modified electrode with immobilized galvinoxyl radical for the voltammetric determination of antioxidant activity / G. Ziyatdinova, Yu. Zelenova, H. Budnikov // J. Electroanal. Chem. – 2020. – V. 586. - Art. � 113677. - 7 p.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=227935&p_lang=2	ru_RU
dc.description.abstract	Journal of Electroanalytical Chemistry	ru_RU
dc.description.abstract	Galvinoxyl radical (GO) immobilized on the electrode surface has been used for the voltammetric determination of antioxidant activity for the first time. Immobilization of radical on glassy carbon electrode (GCE) provides improvement of the system reversibility as well as increase of the redox currents in comparison to GO reduction in solution. But sensitivity of response is insufficient for the antioxidant activity estimation. Application of GCE modified with dispersion of CeO2 nanoparticles (NP) in cationic surfactant cetylpyridinium bromide (CPB) medium (CeO2 NP-CPB/GCE) as a base for GO immobilization provide full reversibility of its reduction (redox currents ratio of 1.02 and peak potential separation of 80 mV) and 7-fold increase of the redox currents at physiological pH of supporting electrolyte. Electrode developed has been successfully applied for the voltammetric evaluation of natural phenolics antioxidant activity expressed as the EC50 parameter (effective concentration of the antioxidant providing 50% inhibition of GO) and antioxidant activity of herbal preparations (tinctures, infusions and decoctions) as relative GO inhibition. Antioxidant activity of natural phenolics is decreased as morin > quercetin = ferulic acid > gallic acid > tannin ≈ catechin. The results obtained agree well with data of standard spectrophotometric method. The advantages of the method developed are 4-fold lower incubation time, less consumption of the reagents and the absence of limitations for colored samples.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Cyclic voltammetry	ru_RU
dc.subject	chemically modified electrodes	ru_RU
dc.subject	galvinoxyl radical	ru_RU
dc.subject	cerium dioxide nanoparticles	ru_RU
dc.subject	antioxidant activity	ru_RU
dc.subject	phytochemical analysis	ru_RU
dc.title	Novel modified electrode with immobilized galvinoxyl radical for the voltammetric determination of antioxidant activity	ru_RU
dc.type	Articles in international journals and collections	ru_RU