Form of presentation | Articles in Russian journals and collections |
Year of publication | 2018 |
Язык | русский |
|
Kadyrova Elvira Rafikovna, author
|
Bibliographic description in the original language |
ANTIBIOTIKOREZISTENTNOST STAPHYLOCOCCUS AUREUS I
PSEUDOMONAS AERUGINOSA NA MODELI MUKOVISCIDOZA KAK
KhRONIChESKOGO ZABOLEVANIYa BRONKhOLEGOChNOY SISTEMY
? Source: Pediatriya named after G. N. Speransky . mar/apr2018, Vol. 97 Issue 2, p176-186. 11p.
? Author(s): Zakirov, I. I.; Kadyrova, E. R.; Safina, A. I.; Kayumov, A. R |
Annotation |
The course and prognosis of cystic fibrosis (CF) in many ways depend on the
degree of bronchopulmonary system lesion. Important role in the development of chronic
inflammation in the bronchopulmonary system belongs to conditionally pathogenic
microorganisms. Rational antibiotic therapy (ABT) allows to restrain the natural course
of the disease. How ever, wide spread use of antibiotics (AB) creates problems of
microorganisms' resistance. The article reviews the literature on antibacterial resistance
(ABR) development mechanisms of Staphylococcus aureus and Pseudomonas
aeruginosa, which most often colonize the respiratory tract in CF. Staphylococcus aureus
and Pseudomonas aeruginosa ABR realizes by the mechanisms of natural and acquired
resistance. The acquired resistance of bacteria develops as a result of natural selection
through random mutations and/or through the action of antibacterial drugs.
Microorganisms carry genetic information of resistance to antibiotics by horizontal gene
transfer, which threatens the spread of multidrug resistant bacteria strains. Rational ABT
is a key mechanism for restraining the development of bacteria antibiotic resistance. |
Keywords |
STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA, МУКОВИСЦИДОЗ, CYSTIC FIBROSIS, АНТИБАКТЕРИАЛЬНАЯ РЕЗИСТЕНТНОСТЬ, ANTIBACTERIAL RESISTANCE |
The name of the journal |
Педиатрия. Журнал им. Г.Н. Сперанского
|
Please use this ID to quote from or refer to the card |
https://repository.kpfu.ru/eng/?p_id=216394&p_lang=2 |
Full metadata record ![](https://shelly.kpfu.ru/pdf/picture/arrow_black_right.gif) |
Field DC |
Value |
Language |
dc.contributor.author |
Kadyrova Elvira Rafikovna |
ru_RU |
dc.date.accessioned |
2018-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2018-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2018 |
ru_RU |
dc.identifier.citation |
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И
PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК
ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ
? Source: Pediatriya named after G. N. Speransky . mar/apr2018, Vol. 97 Issue 2, p176-186. 11p.
? Author(s): Закиров, И. И.; Кадырова, Э. Р.; Сафина, А. И.; Каюмов, А. Р |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/eng/?p_id=216394&p_lang=2 |
ru_RU |
dc.description.abstract |
Педиатрия. Журнал им. Г.Н. Сперанского |
ru_RU |
dc.description.abstract |
The course and prognosis of cystic fibrosis (CF) in many ways depend on the
degree of bronchopulmonary system lesion. Important role in the development of chronic
inflammation in the bronchopulmonary system belongs to conditionally pathogenic
microorganisms. Rational antibiotic therapy (ABT) allows to restrain the natural course
of the disease. How ever, wide spread use of antibiotics (AB) creates problems of
microorganisms' resistance. The article reviews the literature on antibacterial resistance
(ABR) development mechanisms of Staphylococcus aureus and Pseudomonas
aeruginosa, which most often colonize the respiratory tract in CF. Staphylococcus aureus
and Pseudomonas aeruginosa ABR realizes by the mechanisms of natural and acquired
resistance. The acquired resistance of bacteria develops as a result of natural selection
through random mutations and/or through the action of antibacterial drugs.
Microorganisms carry genetic information of resistance to antibiotics by horizontal gene
transfer, which threatens the spread of multidrug resistant bacteria strains. Rational ABT
is a key mechanism for restraining the development of bacteria antibiotic resistance. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
STAPHYLOCOCCUS AUREUS |
ru_RU |
dc.subject |
PSEUDOMONAS AERUGINOSA |
ru_RU |
dc.subject |
МУКОВИСЦИДОЗ |
ru_RU |
dc.subject |
CYSTIC FIBROSIS |
ru_RU |
dc.subject |
АНТИБАКТЕРИАЛЬНАЯ РЕЗИСТЕНТНОСТЬ |
ru_RU |
dc.subject |
ANTIBACTERIAL RESISTANCE |
ru_RU |
dc.title |
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ STAPHYLOCOCCUS AUREUS И
PSEUDOMONAS AERUGINOSA НА МОДЕЛИ МУКОВИСЦИДОЗА КАК
ХРОНИЧЕСКОГО ЗАБОЛЕВАНИЯ БРОНХОЛЕГОЧНОЙ СИСТЕМЫ |
ru_RU |
dc.type |
Articles in Russian journals and collections |
ru_RU |
|