KFU. Card publication. Isolate rat heart: Age features

KAZAN
FEDERAL UNIVERSITY

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- 中文
- ES

ISOLATE RAT HEART: AGE FEATURES

Form of presentation

Articles in international journals and collections

Year of publication

2019

Язык

русский

Authors, employees of KFU

Zaripova Railya Irekovna, author

Zefirov Timur Lvovich, author

Ziyatdinova Nafisa Ilgizovna, author

Kupcova Anna Mikhaylovna, author

Leonova Alina Maratovna, author

Sungatullina Milyausha Ildusovna, author

Authors, postgraduates KFU

Leonova Alina Maratovna, postgraduate kfu

Sungatullina Milyausha Ildusovna, postgraduate kfu

Bibliographic description in the original language

Ziyatdinova N.I. Isolate rat heart: Age features / N.I. Ziyatdinova, A.M. Kuptsova, A.M.Galieva, R.I. Zaripova, M.I. Syngatullina, T.L. Zefirov // EurAsian Journal of BioSciences. 2019. - Vol. 13. - № 2. - rr. 1375 - 1381

Annotation

The autonomic nervous system is involved in the regulation and formation of the heart rhythm. Most experimental studies about the influence of the autonomic nervous system on heart activity in ontogenesis were carried out on a whole organism or isolated tissue. An isolated heart by Langendorff can study arrhythmia, coronary vascular function, and can also help to understand the pathophysiology of modern human diseases, such as hypertension, diabetes, heart failure, or ischemia / reperfusion injury. The work is devoted to the study of isolated heart operation parameters according to Langendorff in postnatal ontogenesis with different levels of adrenergic innervation development. The analysis of the results showed that the stabilization of the isolated heart rate located in a perfused solution occurs during the 16th minute on average. The minimum heart rate values were recorded among newborn animals, the maximum heart rate was detected among 21 day old rats. CP stabilization in the studied age groups was recorded at different time intervals. 7 and 21 day old rats demonstrated the stabilization during the 16th minute, and 42 - 100-day old rat demonstrated such stabilization during the 14th minute. The minimum CP values were recorded among 7 and 21 day old rats; the maximum CP indices were found in adult rats. The stabilization of the contraction force among 42 and 100 day old animals was recorded during the 16th minutes. The minimum values of LVP were recorded in adult rats, the maximum values of LVP were found among 42 day old rats.

Keywords

isolated heart, heart rate, coronary flow, sympathetic innervation of heart, rat, postnatal ontogenesis

The name of the journal

EurAsian Journal of BioSciences

URL

http://www.ejobios.org/download/isolate-rat-heart-age-features-7269.pdf

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=213329&p_lang=2

Resource files

File name	Size (MB)	Format
2019_Kupcova_isolate_rat_heart_age_features_.pdf	0,39	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Zaripova Railya Irekovna	ru_RU
dc.contributor.author	Zefirov Timur Lvovich	ru_RU
dc.contributor.author	Ziyatdinova Nafisa Ilgizovna	ru_RU
dc.contributor.author	Kupcova Anna Mikhaylovna	ru_RU
dc.contributor.author	Leonova Alina Maratovna	ru_RU
dc.contributor.author	Sungatullina Milyausha Ildusovna	ru_RU
dc.contributor.author	Leonova Alina Maratovna	ru_RU
dc.contributor.author	Sungatullina Milyausha Ildusovna	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Ziyatdinova N.I. Isolate rat heart: Age features / N.I. Ziyatdinova, A.M. Kuptsova, A.M.Galieva, R.I. Zaripova, M.I. Syngatullina, T.L. Zefirov // EurAsian Journal of BioSciences. 2019. - Vol. 13. - № 2. - рр. 1375 - 1381	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=213329&p_lang=2	ru_RU
dc.description.abstract	EurAsian Journal of BioSciences	ru_RU
dc.description.abstract	The autonomic nervous system is involved in the regulation and formation of the heart rhythm. Most experimental studies about the influence of the autonomic nervous system on heart activity in ontogenesis were carried out on a whole organism or isolated tissue. An isolated heart by Langendorff can study arrhythmia, coronary vascular function, and can also help to understand the pathophysiology of modern human diseases, such as hypertension, diabetes, heart failure, or ischemia / reperfusion injury. The work is devoted to the study of isolated heart operation parameters according to Langendorff in postnatal ontogenesis with different levels of adrenergic innervation development. The analysis of the results showed that the stabilization of the isolated heart rate located in a perfused solution occurs during the 16th minute on average. The minimum heart rate values were recorded among newborn animals, the maximum heart rate was detected among 21 day old rats. CP stabilization in the studied age groups was recorded at different time intervals. 7 and 21 day old rats demonstrated the stabilization during the 16th minute, and 42 - 100-day old rat demonstrated such stabilization during the 14th minute. The minimum CP values were recorded among 7 and 21 day old rats; the maximum CP indices were found in adult rats. The stabilization of the contraction force among 42 and 100 day old animals was recorded during the 16th minutes. The minimum values of LVP were recorded in adult rats, the maximum values of LVP were found among 42 day old rats.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	isolated heart	ru_RU
dc.subject	heart rate	ru_RU
dc.subject	coronary flow	ru_RU
dc.subject	sympathetic innervation of heart	ru_RU
dc.subject	rat	ru_RU
dc.subject	postnatal ontogenesis	ru_RU
dc.title	Isolate rat heart: Age features	ru_RU
dc.type	Articles in international journals and collections	ru_RU