KFU. Card publication. Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly

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THERMALLY INDUCED CYCLIZATION OF L‐ISOLEUCYL‐L‐ALANINE IN SOLID STATE: EFFECT OF DIPEPTIDE STRUCTURE ON REACTION TEMPERATURE AND SELF‐ASSEMBLY

Form of presentation

Articles in international journals and collections

Year of publication

2019

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Authors, employees of KFU

Gerasimov Aleksandr Vladimirovich, author

Gorbachuk Valeriy Vilenovich, author

Ziganshin Marat Akhmedovich, author

Larionov Radik Anatolevich, author

Mukhametzyanov Timur Anvarovich, author

Khayarov Khasan Rafaelevich, author

Bibliographic description in the original language

Ziganshin, M.A., Larionov, R.A., Gerasimov, A.V., Ziganshina, S.A., Klimovitskii, A.E., Khayarov, Kh.R., Mukhametzyanov T.A., Gorbatchuk, V.V. Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly // Journal of Peptide Science. - 2019. - Vol.25, Is.8. - Art. � e3177.

Annotation

Thermal treatment of short‐chain oligopeptides is able to initiate the process oftheir self‐assembly with the formation of organic nanostructures with uniqueproperties. On the other hand, heating can lead to a chemical reaction with theformation of new substances with specific properties and ability to form structureswith different morphology. Therefore, in order to have a desired process, researcherneeds to find its temperature range. In the present work, cyclization ofL‐isoleucyl‐L‐alanine dipeptide in the solid state upon heating was studied. Kinetic parameters ofthis reaction were estimated within the approaches of the nonisothermal kinetics.The correlation between side chain structure of dipeptides and temperature of theircyclization in the solid state was found for the first time. This correlation may beused to predict the temperature, at which dipeptide self‐assembly changes to chem-ical reaction.

Keywords

cyclization of dipeptide, self‐assembly of dipeptide, solid‐state reaction, kinetic analysis, organicnanostructures, structure‐property correlation, NMR

The name of the journal

Journal of Peptide Science

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069517007&doi=10.1002%2fpsc.3177&partnerID=40&md5=7b29e39cf72f4f146594ab2e6fcad156

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=206707&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gerasimov Aleksandr Vladimirovich	ru_RU
dc.contributor.author	Gorbachuk Valeriy Vilenovich	ru_RU
dc.contributor.author	Ziganshin Marat Akhmedovich	ru_RU
dc.contributor.author	Larionov Radik Anatolevich	ru_RU
dc.contributor.author	Mukhametzyanov Timur Anvarovich	ru_RU
dc.contributor.author	Khayarov Khasan Rafaelevich	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Ziganshin, M.A., Larionov, R.A., Gerasimov, A.V., Ziganshina, S.A., Klimovitskii, A.E., Khayarov, Kh.R., Mukhametzyanov T.A., Gorbatchuk, V.V. Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly // Journal of Peptide Science. - 2019. - Vol.25, Is.8. - Art. � e3177.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=206707&p_lang=2	ru_RU
dc.description.abstract	Journal of Peptide Science	ru_RU
dc.description.abstract	Thermal treatment of short‐chain oligopeptides is able to initiate the process oftheir self‐assembly with the formation of organic nanostructures with uniqueproperties. On the other hand, heating can lead to a chemical reaction with theformation of new substances with specific properties and ability to form structureswith different morphology. Therefore, in order to have a desired process, researcherneeds to find its temperature range. In the present work, cyclization ofL‐isoleucyl‐L‐alanine dipeptide in the solid state upon heating was studied. Kinetic parameters ofthis reaction were estimated within the approaches of the nonisothermal kinetics.The correlation between side chain structure of dipeptides and temperature of theircyclization in the solid state was found for the first time. This correlation may beused to predict the temperature, at which dipeptide self‐assembly changes to chem-ical reaction.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	cyclization of dipeptide	ru_RU
dc.subject	self‐assembly of dipeptide	ru_RU
dc.subject	solid‐state reaction	ru_RU
dc.subject	kinetic analysis	ru_RU
dc.subject	organicnanostructures	ru_RU
dc.subject	structure‐property correlation	ru_RU
dc.subject	NMR	ru_RU
dc.title	Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly	ru_RU
dc.type	Articles in international journals and collections	ru_RU