KFU. Card publication. Selective voltammetric determination of α-lipoic acid on the electrode modified with SnO2 nanoparticles and cetyltriphenylphosphonium bromide

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SELECTIVE VOLTAMMETRIC DETERMINATION OF α-LIPOIC ACID ON THE ELECTRODE MODIFIED WITH SNO2 NANOPARTICLES AND CETYLTRIPHENYLPHOSPHONIUM BROMIDE

Form of presentation

Articles in international journals and collections

Year of publication

2019

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Authors, employees of KFU

Budnikov German Konstantinovich, author

Vorobev Vyacheslav Valerevich, author

Ziyatdinova Guzel Kamilevna, author

Osin Yuriy Nikolaevich, author

Authors, students KFU

Antonova Tatyana Sergeevna, author

Bibliographic description in the original language

Ziyatdinova, G. Selective voltammetric determination of α-lipoic acid on the electrode modified with SnO2 nanoparticles and cetyltriphenylphosphonium bromide / G. Ziyatdinova, T. Antonova, V. Vorobev, Y. Osin, H. Budnikov // Monatsh. Chem. – 2019. – V. 150. – � 3. – P. 401-410.

Annotation

Sensitive voltammetric method for α-lipoic acid determination based on glassy carbon electrode (GCE) modified with SnO2 nanoparticles (SnO2 NP) dispersion in cetyltriphenylphosphonium bromide (CTPPB) (SnO2 NP-CTPPB/GCE) has been developed. The comparison to other surface active compounds as dispersive agents has been performed. The electrodes surface has been characterized by scanning electron microscopy, electrochemical impedance spectroscopy, cyclic voltammetry, and chronoamperometry. Statistically significant decrease of charge transfer resistance (10.8 ? 0.4 kΩ vs. 181 ? 7 kΩ for GCE and 71 ? 3 kΩ for SnO2 NP-H2O/GCE) and higher effective surface area (13.7 ? 0.2 mm2 vs. 8.2 ? 0.3 mm2 for GCE and 12.1 ? 0.2 mm2 for SnO2 NP-H2O/GCE) has been obtained for SnO2 NP-CTPPB/GCE. α-Lipoic acid oxidation on SnO2 NP-CTPPB/GCE is a two-electron diffusion-controlled pH independent process leading to β-lipoic acid formation. Under conditions of differential pulse voltammetry in Britton–Robinson buffer pH 4.5, the linear dynamic ranges are 0.50–50 and 50–400 μmol dm−3 of α-lipoic acid with the limits of detection and quantification of 0.13 and 0.43 μmol dm−3, respectively. The method developed has been successfully applied for the pharmaceutical dosage form analysis.

Keywords

Voltammetry, chemically modified electrodes, metal oxide nanoparticles, surface active compounds, α-lipoic acid

The name of the journal

MONATSHEFTE FUR CHEMIE

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061341323&doi=10.1007%2fs00706-018-2341-5&partnerID=40&md5=faac5f1d57fce4a24b3f257052e0690e

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=196531&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Budnikov German Konstantinovich	ru_RU
dc.contributor.author	Vorobev Vyacheslav Valerevich	ru_RU
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.contributor.author	Osin Yuriy Nikolaevich	ru_RU
dc.contributor.author	Antonova Tatyana Sergeevna	ru_RU
dc.date.accessioned	2019-01-01T00:00:00Z	ru_RU
dc.date.available	2019-01-01T00:00:00Z	ru_RU
dc.date.issued	2019	ru_RU
dc.identifier.citation	Ziyatdinova, G. Selective voltammetric determination of α-lipoic acid on the electrode modified with SnO2 nanoparticles and cetyltriphenylphosphonium bromide / G. Ziyatdinova, T. Antonova, V. Vorobev, Y. Osin, H. Budnikov // Monatsh. Chem. – 2019. – V. 150. – � 3. – P. 401-410.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=196531&p_lang=2	ru_RU
dc.description.abstract	MONATSHEFTE FUR CHEMIE	ru_RU
dc.description.abstract	Sensitive voltammetric method for α-lipoic acid determination based on glassy carbon electrode (GCE) modified with SnO2 nanoparticles (SnO2 NP) dispersion in cetyltriphenylphosphonium bromide (CTPPB) (SnO2 NP-CTPPB/GCE) has been developed. The comparison to other surface active compounds as dispersive agents has been performed. The electrodes surface has been characterized by scanning electron microscopy, electrochemical impedance spectroscopy, cyclic voltammetry, and chronoamperometry. Statistically significant decrease of charge transfer resistance (10.8 ? 0.4 kΩ vs. 181 ? 7 kΩ for GCE and 71 ? 3 kΩ for SnO2 NP-H2O/GCE) and higher effective surface area (13.7 ? 0.2 mm2 vs. 8.2 ? 0.3 mm2 for GCE and 12.1 ? 0.2 mm2 for SnO2 NP-H2O/GCE) has been obtained for SnO2 NP-CTPPB/GCE. α-Lipoic acid oxidation on SnO2 NP-CTPPB/GCE is a two-electron diffusion-controlled pH independent process leading to β-lipoic acid formation. Under conditions of differential pulse voltammetry in Britton–Robinson buffer pH 4.5, the linear dynamic ranges are 0.50–50 and 50–400 μmol dm−3 of α-lipoic acid with the limits of detection and quantification of 0.13 and 0.43 μmol dm−3, respectively. The method developed has been successfully applied for the pharmaceutical dosage form analysis.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Voltammetry	ru_RU
dc.subject	chemically modified electrodes	ru_RU
dc.subject	metal oxide nanoparticles	ru_RU
dc.subject	surface active compounds	ru_RU
dc.subject	α-lipoic acid	ru_RU
dc.title	Selective voltammetric determination of α-lipoic acid on the electrode modified with SnO2 nanoparticles and cetyltriphenylphosphonium bromide	ru_RU
dc.type	Articles in international journals and collections	ru_RU