KFU. Card publication. Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series

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FEDERAL UNIVERSITY

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SYNTHESIS AND ANTIFUNGAL ACTIVITY OF β-HYDROXYSULFIDES OF 1,3-DIOXEPANE SERIES

Form of presentation

Articles in international journals and collections

Year of publication

2018

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Authors, employees of KFU

Gnezdilov Oleg Ivanovich, author

Pavelev Roman Sergeevich, author

Chmutova Galina Alekseevna, author

Bibliographic description in the original language

Pavelyev R.S, Vafina R.M, Balakin K.V, Synthesis and Antifungal Activity of ? -Hydroxysulfides of 1,3-Dioxepane Series//Journal of Chemistry. - 2018. - Vol.2018, Is.. - Art. � 3589342.

Annotation

Synthesis of β-hydroxysulfides of 1,3-dioxepane series and their further functionalization were performed. Chiral β-hydroxysulfides were separated into enantiomers using enzymatic acylation by lipase PS. Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates.

Keywords

β-Hydroxysulfides, organic synthesis, antifungal activity

The name of the journal

Journal of Chemistry

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85056595073&doi=10.1155%2f2018%2f3589342&partnerID=40&md5=6ec0272009549c9215b26140e65eff8b

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=190853&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gnezdilov Oleg Ivanovich	ru_RU
dc.contributor.author	Pavelev Roman Sergeevich	ru_RU
dc.contributor.author	Chmutova Galina Alekseevna	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Pavelyev R.S, Vafina R.M, Balakin K.V, Synthesis and Antifungal Activity of ? -Hydroxysulfides of 1,3-Dioxepane Series//Journal of Chemistry. - 2018. - Vol.2018, Is.. - Art. � 3589342.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=190853&p_lang=2	ru_RU
dc.description.abstract	Journal of Chemistry	ru_RU
dc.description.abstract	Synthesis of β-hydroxysulfides of 1,3-dioxepane series and their further functionalization were performed. Chiral β-hydroxysulfides were separated into enantiomers using enzymatic acylation by lipase PS. Study of antifungal activity of the obtained compounds showed that some enantiomerically pure 6-arylthio-1,3-dioxepan-5-ols represent promising antifungal drug candidates.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	β-Hydroxysulfides	ru_RU
dc.subject	organic synthesis	ru_RU
dc.subject	antifungal activity	ru_RU
dc.title	Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series	ru_RU
dc.type	Articles in international journals and collections	ru_RU