KFU. Card publication. Evaluation of mutagenic and antimutagenic potential of stem bark aqueous extracts of eight trees by the bacterial reverse mutation assay

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EVALUATION OF MUTAGENIC AND ANTIMUTAGENIC POTENTIAL OF STEM BARK AQUEOUS EXTRACTS OF EIGHT TREES BY THE BACTERIAL REVERSE MUTATION ASSAY

Form of presentation

Articles in Russian journals and collections

Year of publication

2018

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Authors, employees of KFU

Ilinskaya Olga Nikolaevna, author

Karamova Nazira Sunagatovna, author

Other authors

Abdul-Hafeez Essam , author

Bibliographic description in the original language

Abdul-Hafeez E.Y. Evaluation of mutagenic and antimutagenic potential of stem bark aqueous extracts of eight trees by the bacterial reverse mutation assay/ E.Y. Abdul-Hafeez, N.S. Karamova , O.N. Ilinskaya //Ecological Genetics. - 2018. – V.16 (3). – P. 55 – 61.

Annotation

Stem bark aqueous extracts of eight woody plants Brachychiton populneus, Ceiba pentandra, Bombax malabaricum, Chorisia speciosa, Albizia lebbeck, Bauhinia variegata, Kigelia africana and Pinus halepensis were tested for their mutagenic and antimutagenic potential in the Ames test with Salmonella typhimurium strains TA98 and TA100. The aqueous extracts were neither toxic nor mutagenic in S. typhimurium tester strains. All of the tested extracts showed detectable antimutagenic effect towards the direct acting mutagens 2-nitrofluorene (2-NF) in TA98 as well as sodium azide in TA100. The extract from Kigelia africana was the most effective in reducing the mutagenicity caused by the direct mutagen 2-NF in the TA98 with 85.42% inhibition rate. A. lebbeck stem bark extract demonstrated the highest antimutagenic activity reducing the base substitution mutations rate for strain TA100 by 94.66% in pre-incubation assay. The results obtained showed that the stem bark aqueous extracts tested can pr

Keywords

mutagenicity, antimutagenicity, medicinal plants, Ames test, Salmonella typhimurium strains, stem bark extracts.

The name of the journal

Ecological genetics

URL

https://journals.eco-vector.com/ecolgenet/article/view/9053/pdf

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=190659&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ilinskaya Olga Nikolaevna	ru_RU
dc.contributor.author	Karamova Nazira Sunagatovna	ru_RU
dc.contributor.author	Abdul-Hafeez Essam	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Abdul-Hafeez E.Y. Evaluation of mutagenic and antimutagenic potential of stem bark aqueous extracts of eight trees by the bacterial reverse mutation assay/ E.Y. Abdul-Hafeez, N.S. Karamova , O.N. Ilinskaya //Ecological Genetics. - 2018. – V.16 (3). – P. 55 – 61.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=190659&p_lang=2	ru_RU
dc.description.abstract	Ecological genetics	ru_RU
dc.description.abstract	Stem bark aqueous extracts of eight woody plants Brachychiton populneus, Ceiba pentandra, Bombax malabaricum, Chorisia speciosa, Albizia lebbeck, Bauhinia variegata, Kigelia africana and Pinus halepensis were tested for their mutagenic and antimutagenic potential in the Ames test with Salmonella typhimurium strains TA98 and TA100. The aqueous extracts were neither toxic nor mutagenic in S. typhimurium tester strains. All of the tested extracts showed detectable antimutagenic effect towards the direct acting mutagens 2-nitrofluorene (2-NF) in TA98 as well as sodium azide in TA100. The extract from Kigelia africana was the most effective in reducing the mutagenicity caused by the direct mutagen 2-NF in the TA98 with 85.42% inhibition rate. A. lebbeck stem bark extract demonstrated the highest antimutagenic activity reducing the base substitution mutations rate for strain TA100 by 94.66% in pre-incubation assay. The results obtained showed that the stem bark aqueous extracts tested can pr	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	mutagenicity	ru_RU
dc.subject	antimutagenicity	ru_RU
dc.subject	medicinal plants	ru_RU
dc.subject	Ames test	ru_RU
dc.subject	Salmonella typhimurium strains	ru_RU
dc.subject	stem bark extracts.	ru_RU
dc.title	Evaluation of mutagenic and antimutagenic potential of stem bark aqueous extracts of eight trees by the bacterial reverse mutation assay	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU