KFU. Card publication. Tiny Rare-Earth Fluoride Nanoparticles Activate Tumour Cell Growth via Electrical Polar Interactions

KAZAN
FEDERAL UNIVERSITY

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TINY RARE-EARTH FLUORIDE NANOPARTICLES ACTIVATE TUMOUR CELL GROWTH VIA ELECTRICAL POLAR INTERACTIONS

Form of presentation

Articles in Russian journals and collections

Year of publication

2018

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Authors, employees of KFU

Kefalas Konstantinos Alkiviadis , author

Nizamutdinov Aleksey Sergeevich, author

Pudovkin Maksim Sergeevich, author

Sarantopulu Evangelia , author

Semashko Vadim Vladimirovich, author

Ferraro Andzhelo , author

Other authors

Gavriil Vassilios , author

Kollia Zoe , author

Bibliographic description in the original language

Semashko V.V. Tiny Rare-Earth Fluoride Nanoparticles Activate Tumour Cell Growth via Electrical Polar Interactions / V.V. Semashko, M.S. Pudovkin, A.C Cefalas, P.V. Zelenikhin, V. E. Gavriil, A. S. Nizamutdinov, Z. Kollia, A. Ferraro, E. Sarantopoulou //Nanoscale Research Letters. - 2018. - 13:370

Annotation

Keywords

Physics of cancer, Tumorigenesis, Cancer and nanoparticles, Mechanotransducers, Mechanosensors, Integrins, EGFR, Nanotechnology, Biosurfaces, Atomic force microscopy, Electrical dipole interactions

The name of the journal

NANOSCALE RESEARCH LETTERS

URL

https://rdcu.be/bbNK7

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=190620&p_lang=2

Resource files

File name	Size (MB)	Format
Semashko_et_al_2018_Nanoscale_Research_Letters.pdf	4,62	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kefalas Konstantinos Alkiviadis	ru_RU
dc.contributor.author	Nizamutdinov Aleksey Sergeevich	ru_RU
dc.contributor.author	Pudovkin Maksim Sergeevich	ru_RU
dc.contributor.author	Sarantopulu Evangelia	ru_RU
dc.contributor.author	Semashko Vadim Vladimirovich	ru_RU
dc.contributor.author	Ferraro Andzhelo	ru_RU
dc.contributor.author	Gavriil Vassilios	ru_RU
dc.contributor.author	Kollia Zoe	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Semashko V.V. Tiny Rare-Earth Fluoride Nanoparticles Activate Tumour Cell Growth via Electrical Polar Interactions / V.V. Semashko, M.S. Pudovkin, A.C Cefalas, P.V. Zelenikhin, V. E. Gavriil, A. S. Nizamutdinov, Z. Kollia, A. Ferraro, E. Sarantopoulou //Nanoscale Research Letters. - 2018. - 13:370	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=190620&p_lang=2	ru_RU
dc.description.abstract	NANOSCALE RESEARCH LETTERS	ru_RU
dc.description.abstract	-	ru_RU
dc.description.abstract	Localised extracellular interactions between nanoparticles and transmembrane signal receptors may well activate cancer cell growth. Herein, tiny LaF3 and PrF3 nanoparticles in DMEM+FBS suspensions stimulated tumour cell growth in three different human cell lines (A549, SW837 and MCF7). Size distribution of nanoparticles, activation of AKT and ERK signalling pathways and viability tests pointed to mechanical stimulation of ligand adhesion binding sites of integrins and EGFR via a synergistic action of an ensemble of tiny size nanoparticles (< 10 nm). While tiny size nanoparticles may be well associated with the activation of EGFR, integrin interplay with nanoparticles remains a multifaceted issue. A theoretical motif shows that, within the requisite pN force scale, each ligand adhesion binding site can be activated by a tiny size dielectric nanoparticle via electrical dipole interaction. The size of the active nanoparticle stayed specified by the amount of the surface charges on the lig	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Physics of cancer	ru_RU
dc.subject	Tumorigenesis	ru_RU
dc.subject	Cancer and nanoparticles	ru_RU
dc.subject	Mechanotransducers	ru_RU
dc.subject	Mechanosensors	ru_RU
dc.subject	Integrins	ru_RU
dc.subject	EGFR	ru_RU
dc.subject	Nanotechnology	ru_RU
dc.subject	Biosurfaces	ru_RU
dc.subject	Atomic force microscopy	ru_RU
dc.subject	Electrical dipole interactions	ru_RU
dc.title	Tiny Rare-Earth Fluoride Nanoparticles Activate Tumour Cell Growth via Electrical Polar Interactions	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU