Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
TITLE GENETIC TESTING TO GUIDE WARFARIN DOSAGE IN RUSSIAN FEDERATION
Form of presentationConference proceedings in international journals and collections
Year of publication2018
  • Gusev Oleg Aleksandrovich, author
  • Shagimardanova Elena Ilyasovna, author
  • Other authors Nikitin Aleksey Georgievich
  • Ananeva Anastasiya Viktorovna, postgraduate kfu
  • Shigapova Leylya Khuzzatovna, postgraduate kfu
  • Bibliographic description in the original language Ananeva, A. Genetic testing to guide warfarin dosage in Russian Federation / A.Ananeva, L.Shigapova, A.Nikitin, M.Gordiev, E.Shagimardanova // Abstracts of the 52nd Annual Scientific Meeting of the European Society for Clinical Investigation "Precision medicine for healthy ageing". - 2018. - V.48. - I.1. - P.135.
    Annotation Warfarin is widely prescribed anticoagulant in thromboembolic disorders, that acts by reducing the activity of vitamin K-dependent clotting factors. The dose of warfarin should be adapted for each patient, based on individual properties and measurements: weight, height, ethnic background and presence of SNPs in genes involved in warfarin metabolism. In this study, we aimed to determine the frequency of clinically relevant SNP in CYP2C9 and VKORC1 in population of Tatarstan region in Russian Federation.
    Keywords warfarin, polymorphism, next-generation sequencing (NGS)
    Place of publication Барселона
    Publishing house John Wiley & Sons Ltd
    URL https://onlinelibrary.wiley.com/toc/13652362/2018/48/S1
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=182660&p_lang=2

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