KFU. Card publication. Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart

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FEDERAL UNIVERSITY

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EFFECT OF NEUROPEPTIDE Y ON ACTION POTENTIAL GENERATION IN WORKING CARDIOMYOCYTES OF THE RIGHT ATRIUM IN RAT HEART

Form of presentation

Articles in Russian journals and collections

Year of publication

2018

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Authors, employees of KFU

Anikina Tatyana Andreevna, author

Zefirov Timur Lvovich, author

Iskakov Nikita Georgievich, author

Other authors

Zefirov Andrey Lvovich, author

Authors, postgraduates KFU

Iskakov Nikita Georgievich, postgraduate kfu

Bibliographic description in the original language

Zverev A. A. Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart / Zverev A.A., Anikina T.A., Iskakov N.G., Zefirov A. L., Zefirov T. L. // Byulleten' Eksperimental'noi Biologii i Meditsiny. - 2018. - Vol. 165, No. 5, pp. 550-552.

Annotation

We studied the effect of neuropeptide Y in concentrations of 10—8-10—6 M on electrical activity of adult rat right atrial cardiomyocytes with preserved spontaneous activity. Neuropeptide Y was found to modulate the amplitude-time parameters of action potential: in concentrations of 10—7 and 10—6 M it reduced the membrane potential, increased the amplitude of action potential and duration of the repolarization phase, and reduced the frequency of action potential generation. In concentration of 10—6 M, neuropeptide Y produced stronger effect on the analyzed parameters, while in concentration of 10—8 M it produced no significant changes.

Keywords

neuropeptide Y; action potential; membrane potential; cardiomyocytes; rat

The name of the journal

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URL

https://link.springer.com/epdf/10.1007/s10517-018-4224-5?author_access_token=dSxvMmK7ysOTx6ZIqvguave4RwlQNchNByi7wbcMAY6eGScfgRupIBn5DBldSWHC1w9--8u7VsyahbGEa1chYXATjZd_RCE475kXQKCmXu9K9QljVO7hslWbtQZ83gyNUFONqF0I3wczfWYEEKq4yA%3D%3D

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=180428&p_lang=2

Resource files

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F_Zverev_et_al_2018_Bulletin_of_Experimental_Biology_and_Medicine__1_.pdf	0,40	pdf	show / download

Full metadata record

Field DC	Value	Language
dc.contributor.author	Anikina Tatyana Andreevna	ru_RU
dc.contributor.author	Zefirov Timur Lvovich	ru_RU
dc.contributor.author	Iskakov Nikita Georgievich	ru_RU
dc.contributor.author	Zefirov Andrey Lvovich	ru_RU
dc.contributor.author	Iskakov Nikita Georgievich	ru_RU
dc.date.accessioned	2018-01-01T00:00:00Z	ru_RU
dc.date.available	2018-01-01T00:00:00Z	ru_RU
dc.date.issued	2018	ru_RU
dc.identifier.citation	Zverev A. A. Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart / Zverev A.A., Anikina T.A., Iskakov N.G., Zefirov A. L., Zefirov T. L. // Byulleten' Eksperimental'noi Biologii i Meditsiny. - 2018. - Vol. 165, No. 5, pp. 550-552.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=180428&p_lang=2	ru_RU
dc.description.abstract	��	ru_RU
dc.description.abstract	We studied the effect of neuropeptide Y in concentrations of 10—8-10—6 M on electrical activity of adult rat right atrial cardiomyocytes with preserved spontaneous activity. Neuropeptide Y was found to modulate the amplitude-time parameters of action potential: in concentrations of 10—7 and 10—6 M it reduced the membrane potential, increased the amplitude of action potential and duration of the repolarization phase, and reduced the frequency of action potential generation. In concentration of 10—6 M, neuropeptide Y produced stronger effect on the analyzed parameters, while in concentration of 10—8 M it produced no significant changes.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject		ru_RU
dc.title	Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart	ru_RU
dc.type	Articles in Russian journals and collections	ru_RU