KFU. Card publication. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

THE EFFECT OF HIGH HYDROSTATIC PRESSURE ON THE VIABILITY AND MUTAGENESIS OF SALMONELLA TYPHIMURIUM

Form of presentation

Articles in international journals and collections

Year of publication

2017

��

��

Authors, employees of KFU

Zelenikhin Pavel Valerevich, author

Ilinskaya Olga Nikolaevna, author

Karamova Nazira Sunagatovna, author

Kiselev Vladimir Dmitrievich, author

Authors, students KFU

Lipatnikova Anastasiya Aleksandrovna, author

Bibliographic description in the original language

Karamova, N.S. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium / N.S. Karamova, P.V. Zelenikhin, V.D. Kiselev, A.A. Lipatnikova, O.N. Ilinskaya // Russian Journal of Genetics: Applied Research. - 2017. - V. 7, No. 6. - P. 698–704.

Annotation

This work is devoted to the study of the influence of high hydrostatic pressure (HHP) on the viability and level of mutagenesis of Salmonella typhimurium. It was established that the viability of bacteria significantly decreases under hydrostatic pressure of 200 MPa or higher. In addition, the viability index of the bacteria is six orders of magnitude lower with respect to the number of colony-forming units (CFUs) compared to the data of the flow cytofluorometry analysis. This is probably due to the transition of some part of the bacterial population to a viable but nonculturable state (VBNC). HHP of 50 MPa caused a 1.9-fold increase in the number of His+ revertants of the S. typhimurium strain TA98, which indicates the potential of the induction of gene mutations under these conditions. The mechanisms to reduce the viability and genetic changes in bacterial cells under HHP conditions are discussed.

Keywords

high hydrostatic pressure, viability, nonculturable state, mutagenesis, mutations, Salmonella typhimurium, flow cytometry, Ames test

The name of the journal

Russian Journal of Genetics: Applied Research

URL

https://link.springer.com/article/10.1134/S2079059717060077

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=172358&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Zelenikhin Pavel Valerevich	ru_RU
dc.contributor.author	Ilinskaya Olga Nikolaevna	ru_RU
dc.contributor.author	Karamova Nazira Sunagatovna	ru_RU
dc.contributor.author	Kiselev Vladimir Dmitrievich	ru_RU
dc.contributor.author	Lipatnikova Anastasiya Aleksandrovna	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Karamova, N.S. The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium / N.S. Karamova, P.V. Zelenikhin, V.D. Kiselev, A.A. Lipatnikova, O.N. Ilinskaya // Russian Journal of Genetics: Applied Research. - 2017. - V. 7, No. 6. - P. 698–704.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=172358&p_lang=2	ru_RU
dc.description.abstract	Russian Journal of Genetics: Applied Research	ru_RU
dc.description.abstract	This work is devoted to the study of the influence of high hydrostatic pressure (HHP) on the viability and level of mutagenesis of Salmonella typhimurium. It was established that the viability of bacteria significantly decreases under hydrostatic pressure of 200 MPa or higher. In addition, the viability index of the bacteria is six orders of magnitude lower with respect to the number of colony-forming units (CFUs) compared to the data of the flow cytofluorometry analysis. This is probably due to the transition of some part of the bacterial population to a viable but nonculturable state (VBNC). HHP of 50 MPa caused a 1.9-fold increase in the number of His+ revertants of the S. typhimurium strain TA98, which indicates the potential of the induction of gene mutations under these conditions. The mechanisms to reduce the viability and genetic changes in bacterial cells under HHP conditions are discussed.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	high hydrostatic pressure	ru_RU
dc.subject	viability	ru_RU
dc.subject	nonculturable state	ru_RU
dc.subject	mutagenesis	ru_RU
dc.subject	mutations	ru_RU
dc.subject	Salmonella typhimurium	ru_RU
dc.subject	flow cytometry	ru_RU
dc.subject	Ames test	ru_RU
dc.title	The Effect of High Hydrostatic Pressure on the Viability and Mutagenesis of Salmonella typhimurium	ru_RU
dc.type	Articles in international journals and collections	ru_RU