Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
NOVEL DRUG TARGETS IN CELL WALL BIOSYNTHESIS EXPLOITED BY GENE DISRUPTION IN PSEUDOMONAS AERUGINOSA
Form of presentationArticles in international journals and collections
Year of publication2017
Языканглийский
  • Shuralev Eduard Arkadevich, author
  • Braun Yvonne , author
  • Elamin Ayssar A. , author
  • Huck Carmen , author
  • Maringer Marko , author
  • Oehlmann Wulf , author
  • Rohde Manfred , author
  • Singh Mahavir , author
  • Steinicke Susanne , author
  • Wanas Hanaa , author
  • Bibliographic description in the original language Elamin A.A. Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa / A.A. Elamin, S. Steinicke, W. Oehlmann, Y. Braun, H. Wanas, E.A. Shuralev, C. Huck, M. Maringer, M. Rohde, M. Singh // PLoS ONE. - 2017. - 12(10): e0186801. DOI: 10.1371/journal.pone.0186801. WOS:000413168100091
    Annotation This study demonstrates that cell wall targets contribute significantly to intracellular survival, in vivo growth, and pathogenesis of P. aeruginosa. In conclusion, these findings establish a link between cell wall targets and virulence of P. aeruginosa and thus may lead to development of novel drugs for the treatment of P. aeruginosa infection.
    Keywords ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, BACTERIAL BIOFILM FORMATION, UDP-N-ACETYLGLUCOSAMINE, ESCHERICHIA-COLI, VIRULENCE FACTORS; LIPOPOLYSACCHARIDE BIOSYNTHESIS; OPPORTUNISTIC PATHOGEN, CRYSTAL-STRUCTURE, ENDOTOXINS, ANTIBIOTICS
    The name of the journal PLos ONE
    On-line resource for training course http://dspace.kpfu.ru/xmlui/bitstream/handle/net/117107/F_Shuralev_Pseudomona.pdf?sequence=1&isAllowed=y
    URL http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186801
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=167144&p_lang=2
    Resource files 
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    F_Shuralev_Pseudomona.pdf 17,55 pdf show / download

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