Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
SYNTHESIS AND ANTITUMOR ACTIVITY OF PYRIDOXINE MONOALKENYL DERIVATIVES
Form of presentationArticles in international journals and collections
Year of publication2016
Языканглийский
  • Pavelev Roman Sergeevich, author
  • Pugachev Mikhail Vladimirovich, author
  • Shtyrlin Yuriy Grigorevich, author
  • Lodochnikova Olga , author
  • Nguen Tkhi Nyat Tkhang, postgraduate kfu
  • Bibliographic description in the original language Pugachev, M.V. Synthesis and antitumor activity of pyridoxine monoalkenyl derivatives / M. V. Pugachev, R. S. Pavelyev, T. N. T. Nguyen, A. G. Iksanova, O. A. Lodochnikova, Yu. G. Shtyrlin // Russian Chemical Bulletin. – 2016. – Vol. 65, I. 2. – P. 532-536.
    Annotation A convenient method for the synthesis of pyridoxine alkenyl derivatives by the Wittig reaction of [(2,8-dimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methyl]triphenylphosphonium chloride with aldehydes was suggested. Some of the compounds obtained exhibit antitumor activity in vitro.
    Keywords alkenyl derivatives, antitumor activity, cytotoxicity, pyridoxine, quaternary phosphonium salts, Wittig reaction
    The name of the journal Russian Chemical Bulletin
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=159581&p_lang=2

    Full metadata record