Form of presentation | Articles in international journals and collections |
Year of publication | 2017 |
Язык | английский |
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Latypova Liliya Zinnurovna, author
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Bibliographic description in the original language |
Latypova, L. Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo / L. Latypova, R. Sibgatullina, A. Ogura, K. Fujiki, A. Khabibrakhmanova, T. Tahara, S. Nozaki, S. Urano, K. Tsubokura, H. Onoe, Y. Watanabe, A. Kurbangalieva, K. Tanaka. // Advanced Science – 2017. – V. 4. – № 2. doi: 10.1002/advs.201600394 |
Annotation |
Two structurally distinct N-glycans were initially united in a single azide-terminated compound that was then immobilized onto albumin via a double click procedure. Noninvasive imaging data revealed that the excretion pathway of the structurally well-defined heterogeneous glycoclusters was not simply a combination of the excretion pathways taken by the homogeneous or arbitrarily arranged heterogeneous glycoclusters. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, played an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms. |
Keywords |
N-glycoalbumin, heterogeneity, pattern recognition, in vivo kinetics, biodistribution, noninvasive fluorescence imaging |
The name of the journal |
Advanced Science
|
Please use this ID to quote from or refer to the card |
https://repository.kpfu.ru/eng/?p_id=151881&p_lang=2 |
Full metadata record ![](https://shelly.kpfu.ru/pdf/picture/arrow_black_right.gif) |
Field DC |
Value |
Language |
dc.contributor.author |
Latypova Liliya Zinnurovna |
ru_RU |
dc.date.accessioned |
2017-01-01T00:00:00Z |
ru_RU |
dc.date.available |
2017-01-01T00:00:00Z |
ru_RU |
dc.date.issued |
2017 |
ru_RU |
dc.identifier.citation |
Latypova, L. Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo / L. Latypova, R. Sibgatullina, A. Ogura, K. Fujiki, A. Khabibrakhmanova, T. Tahara, S. Nozaki, S. Urano, K. Tsubokura, H. Onoe, Y. Watanabe, A. Kurbangalieva, K. Tanaka. // Advanced Science – 2017. – V. 4. – № 2. doi: 10.1002/advs.201600394 |
ru_RU |
dc.identifier.uri |
https://repository.kpfu.ru/eng/?p_id=151881&p_lang=2 |
ru_RU |
dc.description.abstract |
Advanced Science |
ru_RU |
dc.description.abstract |
Two structurally distinct N-glycans were initially united in a single azide-terminated compound that was then immobilized onto albumin via a double click procedure. Noninvasive imaging data revealed that the excretion pathway of the structurally well-defined heterogeneous glycoclusters was not simply a combination of the excretion pathways taken by the homogeneous or arbitrarily arranged heterogeneous glycoclusters. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, played an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms. |
ru_RU |
dc.language.iso |
ru |
ru_RU |
dc.subject |
N-glycoalbumin |
ru_RU |
dc.subject |
heterogeneity |
ru_RU |
dc.subject |
pattern recognition |
ru_RU |
dc.subject |
in vivo kinetics |
ru_RU |
dc.subject |
biodistribution |
ru_RU |
dc.subject |
noninvasive fluorescence imaging |
ru_RU |
dc.title |
Sequential double “clicks” toward structurally well-defined heterogeneous N-glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo |
ru_RU |
dc.type |
Articles in international journals and collections |
ru_RU |
|