Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
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EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF PHOSPHONATES BASED ON THE MODEL OF CHRONIC AUTOIMMUNE INFLAMMATION OF THE PAWS OF RATS.
Form of presentationArticles in international journals and collections
Year of publication2016
Языканглийский
  • Ziganshina Liliya Evgenevna, author
  • Titarenko Albina Faritovna, author
  • Khaziakhmetova Veronika Nikolaevna, author
  • Bibliographic description in the original language Valeeva I. Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats. / Valeeva I., Titarenko A., V.Khaziakhmetova, Ziganshina L. // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2971-2975.
    Annotation Currently, there is an ongoing search for new pharmacological agents capable of exhibiting anti-inflammatory properties in the treatment of chronic autoimmune inflammatory diseases of connective tissue of the movable joints, accompanied by progressive violation of motility of the joints, edema and severe pain, developing joint destruction, disability and disability, particularly in rheumatoid arthritis. Based on white laboratory rats experiments in the modeling of chronic autoimmune inflammation of the paws, similar to the clinical course of chronic autoimmune inflammation of the joints of the human by administering Freund's adjuvant the anti-inflammatory effect of dimephosphone, mephopran, ksidiphone has been evaluated. It has been shown that dimephosphone has an anti-inflammatory effect on the model of chronic autoimmune inflammation of rat paws caused by the administration of Freund's adjuvant. Dimethyl ether of 2-carbometoksipropilphosphonic acid (mephoprane) model of adjuvant arth
    Keywords Freund's adjuvant, dimephosphone, monophosphonate - mephopran (dimethyl ether of 2-carbometoksipropilphosphonic acid) ksidiphone (etidronate), prednisolone
    The name of the journal Research Journal of Pharmaceutical, Biological and Chemical Sciences
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=149214&p_lang=2

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