KFU. Card publication. Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats.

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EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF PHOSPHONATES BASED ON THE MODEL OF CHRONIC AUTOIMMUNE INFLAMMATION OF THE PAWS OF RATS.

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Ziganshina Liliya Evgenevna, author

Titarenko Albina Faritovna, author

Khaziakhmetova Veronika Nikolaevna, author

Bibliographic description in the original language

Valeeva I. Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats. / Valeeva I., Titarenko A., V.Khaziakhmetova, Ziganshina L. // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2971-2975.

Annotation

Currently, there is an ongoing search for new pharmacological agents capable of exhibiting anti-inflammatory properties in the treatment of chronic autoimmune inflammatory diseases of connective tissue of the movable joints, accompanied by progressive violation of motility of the joints, edema and severe pain, developing joint destruction, disability and disability, particularly in rheumatoid arthritis. Based on white laboratory rats experiments in the modeling of chronic autoimmune inflammation of the paws, similar to the clinical course of chronic autoimmune inflammation of the joints of the human by administering Freund's adjuvant the anti-inflammatory effect of dimephosphone, mephopran, ksidiphone has been evaluated. It has been shown that dimephosphone has an anti-inflammatory effect on the model of chronic autoimmune inflammation of rat paws caused by the administration of Freund's adjuvant. Dimethyl ether of 2-carbometoksipropilphosphonic acid (mephoprane) model of adjuvant arth

Keywords

Freund's adjuvant, dimephosphone, monophosphonate - mephopran (dimethyl ether of 2-carbometoksipropilphosphonic acid) ksidiphone (etidronate), prednisolone

The name of the journal

Research Journal of Pharmaceutical, Biological and Chemical Sciences

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=149214&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ziganshina Liliya Evgenevna	ru_RU
dc.contributor.author	Titarenko Albina Faritovna	ru_RU
dc.contributor.author	Khaziakhmetova Veronika Nikolaevna	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Valeeva I. Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats. / Valeeva I., Titarenko A., V.Khaziakhmetova, Ziganshina L. // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2971-2975.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=149214&p_lang=2	ru_RU
dc.description.abstract	Research Journal of Pharmaceutical, Biological and Chemical Sciences	ru_RU
dc.description.abstract	Currently, there is an ongoing search for new pharmacological agents capable of exhibiting anti-inflammatory properties in the treatment of chronic autoimmune inflammatory diseases of connective tissue of the movable joints, accompanied by progressive violation of motility of the joints, edema and severe pain, developing joint destruction, disability and disability, particularly in rheumatoid arthritis. Based on white laboratory rats experiments in the modeling of chronic autoimmune inflammation of the paws, similar to the clinical course of chronic autoimmune inflammation of the joints of the human by administering Freund's adjuvant the anti-inflammatory effect of dimephosphone, mephopran, ksidiphone has been evaluated. It has been shown that dimephosphone has an anti-inflammatory effect on the model of chronic autoimmune inflammation of rat paws caused by the administration of Freund's adjuvant. Dimethyl ether of 2-carbometoksipropilphosphonic acid (mephoprane) model of adjuvant arth	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Freund's adjuvant	ru_RU
dc.subject	dimephosphone	ru_RU
dc.subject	monophosphonate - mephopran (dimethyl ether of 2-carbometoksipropilphosphonic acid) ksidiphone (etidronate)	ru_RU
dc.subject	prednisolone	ru_RU
dc.title	Evaluation of Anti-Inflammatory Activity of Phosphonates Based on the Model of Chronic Autoimmune Inflammation of the Paws of Rats.	ru_RU
dc.type	Articles in international journals and collections	ru_RU