KFU. Card publication. The study of the anti-inflammatory activity of Eforan

KAZAN
FEDERAL UNIVERSITY

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THE STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF EFORAN

Form of presentation

Articles in international journals and collections

Year of publication

2016

Язык

английский

Authors, employees of KFU

Ziganshina Liliya Evgenevna, author

Khaziakhmetova Veronika Nikolaevna, author

Bibliographic description in the original language

Khaziakhmetova V. The study of the anti-inflammatory activity of Eforan / Khaziakhmetova V., Khaziakhmetov D. Valeeva I., Ziganshin A. , Ziganshina L // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2856-2861.

Annotation

Searching for new effective and low-toxic antiphlogistics among the new classes of compounds that could have a selective and prolonged effect and minimum side effects is highly relevant. In this respect, the promising compounds are di- and monophosphonic compounds, which representative is a drug Dimephosphon. Objective of our study was to investigate the influence of Eforan, a new phosphonate, on various models of experimental inflammation, as well as on the development of edema caused by various mediators and modulators of inflammation. In the experiments on rats, Eforan reduced dose-dependently the intensity of the inflammatory reaction caused by carrageenan. The duration of anti-inflammatory action of Eforan was up to 24 hours of observation. Eforan effect on the carrageenan model of inflammation was comparable in the strength of anti-inflammatory effect with acetylsalicylic acid, and differed in longer duration of action. The anti-inflammatory effect of Eforan was demonstrated on t

Keywords

non-steroidal anti-inflammatory drugs, phosphonates, Eforan, inflammation, arthritis, carrageenan, histamine, bradykinin, Freund's adjuvant

The name of the journal

Research Journal of Pharmaceutical, Biological and Chemical Sciences

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=149213&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ziganshina Liliya Evgenevna	ru_RU
dc.contributor.author	Khaziakhmetova Veronika Nikolaevna	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Khaziakhmetova V. The study of the anti-inflammatory activity of Eforan / Khaziakhmetova V., Khaziakhmetov D. Valeeva I., Ziganshin A. , Ziganshina L // Research Journal of Pharmaceutical, Biological and Chemical Sciences - 2016.- 7(6) - pp.2856-2861.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=149213&p_lang=2	ru_RU
dc.description.abstract	Research Journal of Pharmaceutical, Biological and Chemical Sciences	ru_RU
dc.description.abstract	Searching for new effective and low-toxic antiphlogistics among the new classes of compounds that could have a selective and prolonged effect and minimum side effects is highly relevant. In this respect, the promising compounds are di- and monophosphonic compounds, which representative is a drug Dimephosphon. Objective of our study was to investigate the influence of Eforan, a new phosphonate, on various models of experimental inflammation, as well as on the development of edema caused by various mediators and modulators of inflammation. In the experiments on rats, Eforan reduced dose-dependently the intensity of the inflammatory reaction caused by carrageenan. The duration of anti-inflammatory action of Eforan was up to 24 hours of observation. Eforan effect on the carrageenan model of inflammation was comparable in the strength of anti-inflammatory effect with acetylsalicylic acid, and differed in longer duration of action. The anti-inflammatory effect of Eforan was demonstrated on t	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	non-steroidal anti-inflammatory drugs	ru_RU
dc.subject	phosphonates	ru_RU
dc.subject	Eforan	ru_RU
dc.subject	inflammation	ru_RU
dc.subject	arthritis	ru_RU
dc.subject	carrageenan	ru_RU
dc.subject	histamine	ru_RU
dc.subject	bradykinin	ru_RU
dc.subject	Freund's adjuvant	ru_RU
dc.title	The study of the anti-inflammatory activity of Eforan	ru_RU
dc.type	Articles in international journals and collections	ru_RU