KFU. Card publication. Biosensor with Protective Membrane for the Detection of DNA Damage and Antioxidant Properties of Fruit Juices

KAZAN
FEDERAL UNIVERSITY

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BIOSENSOR WITH PROTECTIVE MEMBRANE FOR THE DETECTION OF DNA DAMAGE AND ANTIOXIDANT PROPERTIES OF FRUIT JUICES

Form of presentation

Articles in international journals and collections

Year of publication

2012

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Authors, employees of KFU

Ziyatdinova Guzel Kamilevna, author

Bibliographic description in the original language

Ziyatdinova G. Biosensor with protective membrane for the detection of DNA damage and antioxidant properties of fruit juices / G. Ziyatdinova, J. Labuda // Electroanalysis. 2012. - V.24, � 12. - P.2333-2340

Annotation

With the purpose to prepare a DNA biosensor protected with an outer-sphere membrane against high molecular weight interferences, a carbon film electrode was layer-by-layer modified with dsDNA and chitosan. Using cyclic and square-wave voltammetry and impedance spectroscopy, the oxidative damage of DNA by the hydroxyl and superoxide anion radicals was detected which consists of opening of the helix structure followed by deep DNA chain degradation. The biosensor has been applied to the detection of the antioxidant effect of apple and orange juices. The investigation of the novel biosensor with a protective membrane represents a significant contribution to the field of DNA biosensors utilization.

Keywords

Antioxidants, Biosensors, DNA damage, Electrochemistry, Protective membrane

The name of the journal

ELECTROANALYSIS

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870496862&partnerID=40&md5=c5e776a15062d89fc98cb1276d2e4495

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=142686&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.date.accessioned	2012-01-01T00:00:00Z	ru_RU
dc.date.available	2012-01-01T00:00:00Z	ru_RU
dc.date.issued	2012	ru_RU
dc.identifier.citation	Ziyatdinova G. Biosensor with protective membrane for the detection of DNA damage and antioxidant properties of fruit juices / G. Ziyatdinova, J. Labuda // Electroanalysis. 2012. - V.24, � 12. - P.2333-2340	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=142686&p_lang=2	ru_RU
dc.description.abstract	ELECTROANALYSIS	ru_RU
dc.description.abstract	With the purpose to prepare a DNA biosensor protected with an outer-sphere membrane against high molecular weight interferences, a carbon film electrode was layer-by-layer modified with dsDNA and chitosan. Using cyclic and square-wave voltammetry and impedance spectroscopy, the oxidative damage of DNA by the hydroxyl and superoxide anion radicals was detected which consists of opening of the helix structure followed by deep DNA chain degradation. The biosensor has been applied to the detection of the antioxidant effect of apple and orange juices. The investigation of the novel biosensor with a protective membrane represents a significant contribution to the field of DNA biosensors utilization.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Antioxidants	ru_RU
dc.subject	Biosensors	ru_RU
dc.subject	DNA damage	ru_RU
dc.subject	Electrochemistry	ru_RU
dc.subject	Protective membrane	ru_RU
dc.title	Biosensor with Protective Membrane for the Detection of DNA Damage and Antioxidant Properties of Fruit Juices	ru_RU
dc.type	Articles in international journals and collections	ru_RU