KFU. Card publication. Semaphorins Are likely to Be Involved in the Control of Hibernation

KAZAN
FEDERAL UNIVERSITY

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SEMAPHORINS ARE LIKELY TO BE INVOLVED IN THE CONTROL OF HIBERNATION

Form of presentation

Articles in international journals and collections

Year of publication

2017

Язык

английский

Authors, employees of KFU

Gazizova Guzel Rashitovna, author

Kozlova Olga Sergeevna, author

Nurullin Leniz Faritovich, author

Tyapkina Oksana Viktorovna, author

Shagimardanova Elena Ilyasovna, author

Bibliographic description in the original language

Gazizova G., Kozlova O., Tyapkina O., Nurullin L., Shagimardanova E. Semaphorins Are likely to Be Involved in the Control of Hibernation // BioNanoSci. (2017). doi:10.1007/s12668-016-0292-z

Annotation

Hibernation is unique mammals' phenotype demonstrated surviving in seasonal adverse environment conditions. During hibernation, all of systems of organs undergo alterations in their metabolic activity and physiology similar to different physiological conditions associated with human diseases and injuries, which represent a proper model for studying new approaches in clinical treatment. In this study, we have analyzed expression of semaphorins in small hibernator edible dormouse (Glis glis). Semaphorins are factors which involved in a key process of axon guidance and cell–cell communication and can act as tumor suppressor. We found that gene coding Semaphorin-3D (SEMA3D), previously reported to be specific for brain and heart of mammals, represents one of the most upregulated transcripts in the muscles of the hibernating dormice. Furthermore, another member of the same family, Semaphorin-5B (SEMA5B), was strongly induced in the spinal cord of hibernating animals. These observations make

Keywords

Semaphorin, Hibernation, Edible dormice, Gene expression

The name of the journal

BioNanoScience

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=140066&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gazizova Guzel Rashitovna	ru_RU
dc.contributor.author	Kozlova Olga Sergeevna	ru_RU
dc.contributor.author	Nurullin Leniz Faritovich	ru_RU
dc.contributor.author	Tyapkina Oksana Viktorovna	ru_RU
dc.contributor.author	Shagimardanova Elena Ilyasovna	ru_RU
dc.date.accessioned	2017-01-01T00:00:00Z	ru_RU
dc.date.available	2017-01-01T00:00:00Z	ru_RU
dc.date.issued	2017	ru_RU
dc.identifier.citation	Gazizova G., Kozlova O., Tyapkina O., Nurullin L., Shagimardanova E. Semaphorins Are likely to Be Involved in the Control of Hibernation // BioNanoSci. (2017). doi:10.1007/s12668-016-0292-z	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=140066&p_lang=2	ru_RU
dc.description.abstract	BioNanoScience	ru_RU
dc.description.abstract	Hibernation is unique mammals' phenotype demonstrated surviving in seasonal adverse environment conditions. During hibernation, all of systems of organs undergo alterations in their metabolic activity and physiology similar to different physiological conditions associated with human diseases and injuries, which represent a proper model for studying new approaches in clinical treatment. In this study, we have analyzed expression of semaphorins in small hibernator edible dormouse (Glis glis). Semaphorins are factors which involved in a key process of axon guidance and cell–cell communication and can act as tumor suppressor. We found that gene coding Semaphorin-3D (SEMA3D), previously reported to be specific for brain and heart of mammals, represents one of the most upregulated transcripts in the muscles of the hibernating dormice. Furthermore, another member of the same family, Semaphorin-5B (SEMA5B), was strongly induced in the spinal cord of hibernating animals. These observations make	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Semaphorin	ru_RU
dc.subject	Hibernation	ru_RU
dc.subject	Edible dormice	ru_RU
dc.subject	Gene expression	ru_RU
dc.title	Semaphorins Are likely to Be Involved in the Control of Hibernation	ru_RU
dc.type	Articles in international journals and collections	ru_RU