KFU. Card publication. Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells

KAZAN
FEDERAL UNIVERSITY

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- 中文
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RECENT ADVANCES AND FUTURE DIRECTION IN LYOPHILISATION AND DESICCATION OF MESENCHYMAL STEM CELLS

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Gusev Oleg Aleksandrovich, author

Nesmelov Aleksandr Aleksandrovich, author

Rizvanov Albert Anatolevich, author

Bibliographic description in the original language

Bissoyi A, Kumar A, Rizvanov A.A, Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells//Stem Cells International. - 2016. - Vol.2016, Is.. - Art. � 3604203.

Annotation

Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs. MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions. Current technology of MSCs cryopreservation has significant disadvantages. Alternative technologies of mammalian cells preservation through lyophilisation or desiccation (air-drying) are among the upcoming domains of investigation in the field of cryobiology. Different protectants and their combinations were studied in this context. Loading of the protectant in the live cell can be a challenging issue but recent studies have shown encouraging results. This paper deals with a review of the protectants, methods of their delivery, and physical boundary conditions adopted for the desiccation and lyophilisation of mammalian cells, including MSCs. A hybrid technique combining both methods is also proposed as a promising way of MSCs dry preservation.

Keywords

anhydrobiosis, MSC, dry preservation

The name of the journal

Stem Cells International

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984846490&partnerID=40&md5=4b1a8a5ec39e63cd4cfa7c6448d4228f

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=139005&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Gusev Oleg Aleksandrovich	ru_RU
dc.contributor.author	Nesmelov Aleksandr Aleksandrovich	ru_RU
dc.contributor.author	Rizvanov Albert Anatolevich	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Bissoyi A, Kumar A, Rizvanov A.A, Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells//Stem Cells International. - 2016. - Vol.2016, Is.. - Art. � 3604203.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=139005&p_lang=2	ru_RU
dc.description.abstract	Stem Cells International	ru_RU
dc.description.abstract	Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs. MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions. Current technology of MSCs cryopreservation has significant disadvantages. Alternative technologies of mammalian cells preservation through lyophilisation or desiccation (air-drying) are among the upcoming domains of investigation in the field of cryobiology. Different protectants and their combinations were studied in this context. Loading of the protectant in the live cell can be a challenging issue but recent studies have shown encouraging results. This paper deals with a review of the protectants, methods of their delivery, and physical boundary conditions adopted for the desiccation and lyophilisation of mammalian cells, including MSCs. A hybrid technique combining both methods is also proposed as a promising way of MSCs dry preservation.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	anhydrobiosis	ru_RU
dc.subject	MSC	ru_RU
dc.subject	dry preservation	ru_RU
dc.title	Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells	ru_RU
dc.type	Articles in international journals and collections	ru_RU