KFU. Card publication. Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

EXPLORING THE GLYCAN INTERACTION IN VIVO: FUTURE PROSPECTS OF NEO-GLYCOPROTEINS FOR DIAGNOSTICS

Form of presentation

Articles in international journals and collections

Year of publication

2016

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Authors, employees of KFU

Kurbangalieva Almira Rafaelovna, author

Bibliographic description in the original language

Ogura A. Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics / A. Ogura, A. Kurbangalieva, K. Tanaka // Glycobiology. - 2016. doi: 10.1093/glycob/cww038

Annotation

Herein the biodistributions and in vivo kinetics of chemically prepared neoglycoproteins are reviewed. Chemical methods can be used to conjugate various mono- and oligosaccharides onto a protein surface. The kinetics and organ-specific accumulation profiles of these glycoconjugates, which are introduced through intravenous injections, have been analyzed using conventional dissection studies as well as noninvasive methods such as single photon emission computed tomography, positron emission tomography, and fluorescence imaging. These studies suggest that glycan-dependent protein distribution kinetics may be useful for pharmacological and diagnostic applications.

Keywords

albumin, in vivo imaging, neo-glycoprotein, N-glycans, tumor targeting

The name of the journal

Glycobiology

URL

http://glycob.oxfordjournals.org/content/early/2016/04/14/glycob.cww038.abstract

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=136147&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Kurbangalieva Almira Rafaelovna	ru_RU
dc.date.accessioned	2016-01-01T00:00:00Z	ru_RU
dc.date.available	2016-01-01T00:00:00Z	ru_RU
dc.date.issued	2016	ru_RU
dc.identifier.citation	Ogura A. Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics / A. Ogura, A. Kurbangalieva, K. Tanaka // Glycobiology. - 2016. doi: 10.1093/glycob/cww038	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=136147&p_lang=2	ru_RU
dc.description.abstract	Glycobiology	ru_RU
dc.description.abstract	Herein the biodistributions and in vivo kinetics of chemically prepared neoglycoproteins are reviewed. Chemical methods can be used to conjugate various mono- and oligosaccharides onto a protein surface. The kinetics and organ-specific accumulation profiles of these glycoconjugates, which are introduced through intravenous injections, have been analyzed using conventional dissection studies as well as noninvasive methods such as single photon emission computed tomography, positron emission tomography, and fluorescence imaging. These studies suggest that glycan-dependent protein distribution kinetics may be useful for pharmacological and diagnostic applications.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	albumin	ru_RU
dc.subject	in vivo imaging	ru_RU
dc.subject	neo-glycoprotein	ru_RU
dc.subject	N-glycans	ru_RU
dc.subject	tumor targeting	ru_RU
dc.title	Exploring the glycan interaction in vivo: future prospects of neo-glycoproteins for diagnostics	ru_RU
dc.type	Articles in international journals and collections	ru_RU