Kazan (Volga region) Federal University, KFU
KAZAN
FEDERAL UNIVERSITY
 
UBIQUITIN-PROTEASOME SYSTEM: PROMISING THERAPEUTIC TARGETS IN AUTOIMMUNE AND NEURODEGENERATIVE DISEASES
Form of presentationArticles in international journals and collections
Year of publication2016
Языканглийский
  • Doktor Palotash Andrash Levente , author
  • Rizvanov Albert Anatolevich, author
  • Khaybullina Svetlana Francevna, author
  • Bibliographic description in the original language Bulatov, E., Khaiboullina, S., dos Reis, H.J., Palotás, A., Venkataraman, K., Vijayalakshmi, M., Rizvanov, A. BioNanoSci. (2016). doi:10.1007/s12668-016-0233-x
    Annotation Ubiquitin-proteasome system is emerging as an immensely important enzymatic pathway playing central roles in protein degradation and signaling in numerous human diseases. Building on the prolific success of targeting the ubiquitin-proteasome system in cancer, the broader scientific community is currently seeking to elucidate the potential roles of this enzymatic system in other diseases such as autoimmune and neurodegenerative. A number of promising protein targets for these disorders have been identified in the recent years, and this review briefly summarizes the most recent advances in the field.
    Keywords Ubiquitin-proteasome system, Autoimmunity, Neurodegeneration, Systemic lupus erythematosus, Multiple sclerosis, Parkinson?s disease, Alzheimer?s disease
    The name of the journal BioNanoScience
    URL http://link.springer.com/article/10.1007/s12668-016-0233-x
    Please use this ID to quote from or refer to the card https://repository.kpfu.ru/eng/?p_id=135211&p_lang=2
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