KFU. Card publication. Cyclic voltammetry of natural flavonoids on mwnt-modified electrode and their determination in pharmaceuticals

KAZAN
FEDERAL UNIVERSITY

- RUS
- 中文
- ES

CYCLIC VOLTAMMETRY OF NATURAL FLAVONOIDS ON MWNT-MODIFIED ELECTRODE AND THEIR DETERMINATION IN PHARMACEUTICALS

Form of presentation

Articles in international journals and collections

Year of publication

2011

��

��

Authors, employees of KFU

Budnikov German Konstantinovich, author

Ziyatdinova Guzel Kamilevna, author

Authors, postgraduates KFU

Morozov Mikhail Valerevich, postgraduate kfu

Nizamova Alfiya Maratovna, postgraduate kfu

Authors, students KFU

Aytuganova Ilmira Ilnurovna, author

Bibliographic description in the original language

Ziyatdinova, G. Cyclic voltammetry of natural flavonoids on MWNT-modified electrode and their determination in pharmaceuticals / G. Ziyatdinova, I. Aytuganova, A. Nizamova, M. Morozov, H. Budnikov // Collect. Czech. Chem. Commun. - 2011. - V. 76. - No. 12. - P. 1619-1631.

Annotation

The determination of rutin, quercetin and taxifolin in pharmaceutical dosage forms using cyclic voltammetry on multi-walled carbon nanotube modified glassy carbon electrode (MWNT-GCE) has been developed. The surface of the electrode created has been characterized by atomic force microscopy. Electrode modification with MWNT increases the surface average roughness (190-fold) and structures it. There are two oxidation steps at 0.22 and 0.80, 0.23 and 0.80, 0.26 and 0.86 V on cyclic voltammograms of taxifolin, quercetin and rutin, respectively, in phosphate buffer solution of pH 7.4. The linear dynamic range is 1.4?28 and 28?210, 2.0?220 and 0.52?210 μM with detection limits of 0.71, 1.0 and 0.26 μM for rutin, quercetin and taxifolin, respectively. The relative standard deviation of flavonoids determination in pharmaceuticals does not exceed of 7%. The data obtained are in good agreement with coulometric determination.

Keywords

Carbon nanotubes, chemically modified electrodes, cyclic voltammetry, flavonoids, pharmaceutical analysis

The name of the journal

Collection of Czechoslovak Chemical Communications

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856757909&partnerID=40&md5=ac56f7a6f2546d08613bfa3717648d55

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=134860&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Budnikov German Konstantinovich	ru_RU
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.contributor.author	Aytuganova Ilmira Ilnurovna	ru_RU
dc.contributor.author	Morozov Mikhail Valerevich	ru_RU
dc.contributor.author	Nizamova Alfiya Maratovna	ru_RU
dc.date.accessioned	2011-01-01T00:00:00Z	ru_RU
dc.date.available	2011-01-01T00:00:00Z	ru_RU
dc.date.issued	2011	ru_RU
dc.identifier.citation	Ziyatdinova, G. Cyclic voltammetry of natural flavonoids on MWNT-modified electrode and their determination in pharmaceuticals / G. Ziyatdinova, I. Aytuganova, A. Nizamova, M. Morozov, H. Budnikov // Collect. Czech. Chem. Commun. - 2011. - V. 76. - No. 12. - P. 1619-1631.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=134860&p_lang=2	ru_RU
dc.description.abstract	Collection of Czechoslovak Chemical Communications	ru_RU
dc.description.abstract	The determination of rutin, quercetin and taxifolin in pharmaceutical dosage forms using cyclic voltammetry on multi-walled carbon nanotube modified glassy carbon electrode (MWNT-GCE) has been developed. The surface of the electrode created has been characterized by atomic force microscopy. Electrode modification with MWNT increases the surface average roughness (190-fold) and structures it. There are two oxidation steps at 0.22 and 0.80, 0.23 and 0.80, 0.26 and 0.86 V on cyclic voltammograms of taxifolin, quercetin and rutin, respectively, in phosphate buffer solution of pH 7.4. The linear dynamic range is 1.4?28 and 28?210, 2.0?220 and 0.52?210 μM with detection limits of 0.71, 1.0 and 0.26 μM for rutin, quercetin and taxifolin, respectively. The relative standard deviation of flavonoids determination in pharmaceuticals does not exceed of 7%. The data obtained are in good agreement with coulometric determination.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Carbon nanotubes	ru_RU
dc.subject	chemically modified electrodes	ru_RU
dc.subject	cyclic voltammetry	ru_RU
dc.subject	flavonoids	ru_RU
dc.subject	pharmaceutical analysis	ru_RU
dc.title	Cyclic voltammetry of natural flavonoids on mwnt-modified electrode and their determination in pharmaceuticals	ru_RU
dc.type	Articles in international journals and collections	ru_RU