KFU. Card publication. Surfactant media for constant-current coulometry. Application for the determination of antioxidants in pharmaceuticals

KAZAN
FEDERAL UNIVERSITY

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SURFACTANT MEDIA FOR CONSTANT-CURRENT COULOMETRY. APPLICATION FOR THE DETERMINATION OF ANTIOXIDANTS IN PHARMACEUTICALS

Form of presentation

Articles in international journals and collections

Year of publication

2012

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Authors, employees of KFU

Budnikov German Konstantinovich, author

Ziganshina Endzhe Rishatovna, author

Ziyatdinova Guzel Kamilevna, author

Bibliographic description in the original language

Ziyatdinova, G. Surfactant media for constant-current coulometry. Application for the determination of antioxidants in pharmaceuticals / G. Ziyatdinova, E. Ziganshina, H. Budnikov // Anal. Chim. Acta. - 2012. – V. 744. – P. 23-28.

Annotation

Effect of surfactant presence on electrochemical generation of titrants has been evaluated and discussed for the first time. Cationic (1-dodecylpyridinium and cetylpyridinium bromide), anionic (sodium dodecylsulfate) and nonionic (Triton X100 and Brij? 35) surfactants as well as nonionic high molecular weight polymer (PEG 4000) do not react with the electrogenerated bromine, iodine and hexacyanoferrate(III) ions. The electrogenerated chlorine chemically interact with Triton X100 and Brij? 35. The allowable range of surfactants concentrations providing 100% current yield has been found. Chain-breaking low molecular weight antioxidants (ascorbic acid, rutin, a-tocopherol and retinol) were determined by reaction with the electrogenerated titrants in surfactant media. Simple, express and reliable coulometric approach for determination of a-tocopherol, rutin and ascorbic acid in pharmaceuticals using surfactant media has been developed.

Keywords

Surfactant media, constant-current coulometry, electrogenerated oxidants, antioxidants, pharmaceutical analysis

The name of the journal

Analytica Chimica Acta

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865545953&partnerID=40&md5=daa0746baa1f408dcc9a6ac6cd26eda3

Please use this ID to quote from or refer to the card

https://repository.kpfu.ru/eng/?p_id=134854&p_lang=2

Full metadata record

Field DC	Value	Language
dc.contributor.author	Budnikov German Konstantinovich	ru_RU
dc.contributor.author	Ziganshina Endzhe Rishatovna	ru_RU
dc.contributor.author	Ziyatdinova Guzel Kamilevna	ru_RU
dc.date.accessioned	2012-01-01T00:00:00Z	ru_RU
dc.date.available	2012-01-01T00:00:00Z	ru_RU
dc.date.issued	2012	ru_RU
dc.identifier.citation	Ziyatdinova, G. Surfactant media for constant-current coulometry. Application for the determination of antioxidants in pharmaceuticals / G. Ziyatdinova, E. Ziganshina, H. Budnikov // Anal. Chim. Acta. - 2012. – V. 744. – P. 23-28.	ru_RU
dc.identifier.uri	https://repository.kpfu.ru/eng/?p_id=134854&p_lang=2	ru_RU
dc.description.abstract	Analytica Chimica Acta	ru_RU
dc.description.abstract	Effect of surfactant presence on electrochemical generation of titrants has been evaluated and discussed for the first time. Cationic (1-dodecylpyridinium and cetylpyridinium bromide), anionic (sodium dodecylsulfate) and nonionic (Triton X100 and Brij? 35) surfactants as well as nonionic high molecular weight polymer (PEG 4000) do not react with the electrogenerated bromine, iodine and hexacyanoferrate(III) ions. The electrogenerated chlorine chemically interact with Triton X100 and Brij? 35. The allowable range of surfactants concentrations providing 100% current yield has been found. Chain-breaking low molecular weight antioxidants (ascorbic acid, rutin, a-tocopherol and retinol) were determined by reaction with the electrogenerated titrants in surfactant media. Simple, express and reliable coulometric approach for determination of a-tocopherol, rutin and ascorbic acid in pharmaceuticals using surfactant media has been developed.	ru_RU
dc.language.iso	ru	ru_RU
dc.subject	Surfactant media	ru_RU
dc.subject	constant-current coulometry	ru_RU
dc.subject	electrogenerated oxidants	ru_RU
dc.subject	antioxidants	ru_RU
dc.subject	pharmaceutical analysis	ru_RU
dc.title	Surfactant media for constant-current coulometry. Application for the determination of antioxidants in pharmaceuticals	ru_RU
dc.type	Articles in international journals and collections	ru_RU